This study investigates the effect in rats of acute CdCl(2) (5 microM) intoxication on renal function and characterizes the transport of Ca(2+), Cd(2+), and Zn(2+) in the proximal tubule (PT), loop of Henle (LH), and terminal segments of the nephron (DT) using whole kidney clearance and nephron microinjection techniques. Acute Cd(2+) injection resulted in renal losses of Na(+), K(+), Ca(2+), Mg...

In this work, an efficient photocatalyst based on gamma-cyclodextrin-modified titanium dioxide nanoparticles (TiO2/γ-CD NPs) was synthesized and used for photocatalytic degradation of rhodamine B (RhB), methyl orange (MO) and methylene blue (MB). The results of FESEM, EDX, TEM, FT-IR, XRD and BET surface area measurement showed that the TiO2 NPs were effectively modifi...

The CD2 glycoprotein has been implicated in both positive ment of positive selection, the lack of CD2 was associated and negative regulation of T-cell mitogenesis. To study the with defects in proliferative responses and interferon-g proinvolvement of CD2 in T-lymphocyte development and imduction when transgenic thymocytes and mature T lymphomune responses, we have analyzed two lines of CD2-nul...

An Mn(2+) and Cd(2+) uptake gene, mntA, was cloned from Lactobacillus plantarum ATCC 14917 into Escherichia coli. Its expression conferred on E. coli cells increased Cd(2+) sensitivity as well as energy-dependent Cd(2+) uptake activity. Both transcription and translation of mntA were induced by Mn(2+) starvation in L. plantarum, as indicated by reverse transcriptase PCR and immunoblotting. Two ...

Bioaccumulation of Cd(2+) in soil bacteria might represent an important route of metal transfer to associated mycorrhizal fungi and plants and may have potential as a tool to accelerate Cd(2+) extraction in the bioremediation of contaminated soils. The present study examined the bioaccumulation of Cd(2+) in 15 bacterial strains representing three phyla (Firmicutes, Proteobacteria, and Bacteroid...

Cd(2+) causes damages to several human tissues. Although the toxicological and carcinogenetic mechanisms of Cd(2+) have been previously established, some basic questions on this toxicant remain unclear. In this study, we constructed Met-cad 1.57, a new fluorescent resonance energy transfer (FRET)-based Cd(2+) indicator, which contains a portion of a Cd(2+)-binding protein (CadR) obtained from P...

Cadmium (Cd) isotopes are an important tool to better understand the inorganic and organic geochemistry of Cd. Organic ligands play a key role control toxicity mobility Cd in living organisms also terrestrial aquatic environments. Therefore, knowledge equilibrium isotope fractionation with is crucial further advance source process tracing field biogeochemistry. In this study, we calculated redu...