BACKGROUND Mucosal healing (MH) is a vital early endpoint in management of Crohn's disease (CD). MH depends on endoscopic assessment and there is increasing interest in non-invasive proxies, Pediatric Crohn's Disease activity Index (PDCAI), C-reactive protein (CRP) and fecal calprotectin (FC). These proxies must be validated against endoscopic disease activity (SES-CD) at diagnosis and after in...

BACKGROUND AND AIMS A genetically impaired intestinal barrier function has long been suspected to be a predisposing factor for Crohn's disease (CD). Recently, mutations of the capsase recruitment domain family, member 15 (CARD15) gene have been identified and associated with CD. We hypothesise that a CARD15 mutation may be associated with an impaired intestinal barrier. METHODS We studied 128...

Pot experiments were conducted to investigate the role of dissolved organic matter (DOM) in the Cd speciation in the rhizosphere of hyperaccumulating ecotype (HE) and non-hyperaccumulating ecotype (NHE) of Sedum alfredii and its effects on Cd mobility. After growing HE S. alfredii, the rhizosphere soil solution pH of heavily polluted soil (HPS) and slightly polluted soil (SPS) was reduced by 0....

Background and aim: A genetically impaired intestinal barrier function has long been suspected to be a predisposing factor for Crohn’s disease (CD). Recently, mutations of the capsase recruitment domain family, member 15 (CARD15) gene have been identified and associated with CD. We hypothesise that a CARD15 mutation may be associated with an impaired intestinal barrier. Methods: We studied 128 ...

Cytidine deaminase (CD), a cytoplasmic enzyme, is thought to leak out of damaged cells and can be measured in fluids by a simple biochemical assay. This study has shown that serum CD activity is raised in rheumatoid arthritis (RA) compared with osteoarthritis (OA). Synovial fluid (SF) CD activity was always less than the corresponding serum activity (mean SF/serum ratio = 0.6) in OA but up to 2...

R esum e Dans cet article nous etudions des questions extr emales pour le treillis r-cubique. Pour cela, nous g en eralisons l'index cd du treillis cubique a un index r-cd, que nous appellons (r). Les coeecients de (r) d enombrent les permutations d'Andr e r-sign ees augment ees, g en eralisant d'une mani ere naturelle les r esultats de Purtill qui mettent en rapport l'index cd du trellis cubiq...

Introduction. This study aimed to determine if preoperative psychological tests combined with simple pain prediction ratings could predict pain intensity and analgesic usage following cesarean delivery (CD). Methods. 50 healthy women undergoing scheduled CD with spinal anesthesia comprised the prospective study cohort. Preoperative predictors included 4 validated psychological questionnaires (A...

Proper communication between dorsal caudate (CD) and ventral striatum (VS) is likely to be crucial for on-time responses and its disruption might result in impulsivity. Here, we used functional magnetic resonance imaging (fMRI) with a sensorimotor reaction time task and positron emission tomography (PET) with [(11)C]raclopride in 14 healthy controls and 18 cannabis abusers to contrast the modul...

1. Suppose that R is a UFD. Let a(x) = ca1(x) and b(x) = db1(x) be primitive decompositions of a and b. Then, since p(x) ∈ R[x], we have that cd ∈ R. Now, the leading coefficient of a(x)b(x) is the cd times the product of the leading coefficients of a1(x) ∈ R[x] and b1(x) ∈ R[x]. But since p is monic, all these must units of R. So, without loss of generality, we may assume that a1 and b1 are mo...