conclusions according to our results, silymarin injection caused significant differentiation of mscs to neurons and neuroglia that could be a promising approach for treating a variety of brain injuries. results expression of cd29 and cd90 markers that are characteristic of bmmscs were confirmed by flow cytometry experiments. the data demonstrated that proliferation and number of progenitor cell...

results there was a significant difference in prevalence of ebv presence between patients and controls. the ebv was found by rt-pcr in 19 (63.33%) out of 30 patients and only in eight (26.7%) of 30 control samples. the p = 0.004, was calculated using chi-square test (or: 4.75; 95% ci: 1.58 ‒ 14.25). conclusions our study is the first investigation performed on patients with lch and its possible...

introduction : deproteinized bovine bone mineral (bio-oss) is a xenogenic bone substitute, widely used in maxillofacial bone regeneration. the aim of this in vitro study was to investigate its influence on the growth behavior of human osteosarcoma cell line, saos-2 culture, and compare it with the physiologic dose of dexamethasone, an inductive factor for osteoblasts. materials and methods: hum...

background and objective: the association of ebv with hodgkin lymphoma (hl) has been intensely investigated over the last few years. ebv is also associated with several other malignancies. on the other hand, ki67 molecule serves as a widely accepted proliferation marker. several studies were previously performed about the expression of ki67 in hd. this study tried to detect the correlation betw...

background the mutations of lhbs in pre-s, especially in pre-s2, are definitive in hepatocellular carcinoma (hcc) associated with hbv. however, the mechanisms of the n-glycosylation modification in lhbs are unclear. the n-glycosylation modification of lhbs affects endoplasmic reticulum stress, cell proliferation and its secretion which was further studied. objectives the objectives of our studi...

aim : in this paper effect of combinational usage of calprotectin and etoposide on ags cell line is studied. background : application of combined toxic agents such as etoposide and cicplatin are commonly used for chemotherapy purposes. as a matter of fact, calprotectin and etoposide were both applied on human gastric adenocarcinoma cell line (ags) as antitumor agents. both calprotectin and etop...

back ground: candida albicans is a member of the normal human microflora. c. albicans cell wall is composed of several protein and carbohydrate components which have been shown to play a crucial role in c. albicans interaction with the host immune system. major components of c. albican cell wall are carbohydrates such as mannans, β glucans and chitins, and proteins that partially modulate the h...

aerial parts of salvia mirzayanii was extracted with methanol. methanol extract was suspended in water and defatted with petroleum ether. the defatted part was then partitioned between ethyl acetate and water. the ethyl acetate partition was chromatographed on a silica gel column to afford several fractions. lymphocyte proliferation inhibitory assay of the resulted fractions was compared in vit...

abstract due to their mulitpotency, mesenchymal stem cells (mscs), have the ability to proliferate and differentiate into multiple mesodermal tissues. the aim of this study was to isolate mscs from human umbilical cord (hucmscs) to determine their osteogenic potential on nanofibrous scaffolds. to this end, poly (l-lactic acid) (plla)/nano hydroxyapatite (ha) composite nanofibrous scaffolds were...

background: one area of nanoscience deals with nanoscopic interactions between nanostructured materials and biological systems. to elucidate the effects of the substrate surface morphology and viscoelasticity on cell proliferation, fractal analysis was performed on endothelial cells cultured on nanocomposite samples based on silicone rubber (sr) and various concentrations of organomodified nano...