نتایج جستجو برای: cerebroventricular
تعداد نتایج: 132 فیلتر نتایج به سال:
Background and Purpose—Clinical data suggest that Alzheimer disease (AD) and stroke together potentiate cognitive impairment. Our rat model demonstrates that this interaction may be mediated through inflammatory cells and pathways. Thus, anti-inflammatory agents such as Triflusal, a nonsteroidal anti-inflammatory agent (NSAID), may provide neuroprotection for susceptible neurons in AD and cereb...
The atypical antipsychotic clozapine is very effective for treatment of schizophrenia, but it causes agranulocytosis requiring drug cessation in up to 2% of cases. There has been some success rechallenging with clozapine at a later date or giving granulocyte colony stimulating factor or lithium while continuing clozapine. However, there are still some patients for whom these strategies do not w...
Cranial sonography revealed cerebral hemorrhage in three of seven neonates with erythroblastosis fetalis. Among the three infants with hemorrhage, one was 28 weeks gestational age and experienced germinal matrix hemorrhage with ventricular extension, a finding typical of cerebroventricular hemorrhage in the premature population. The other two infants with intracranial hemorrhage were more gesta...
14 Abstract Administration of the long form (38 amino acids) 15 of pituitary adenylate cyclase-activating polypeptide 16 (PACAP38) into the central nervous system causes hyperther17 mia, suggesting that PACAP38 plays a role in the regulation of 18 deep body temperature (Tb). In this study, we investigated the 19 thermoregulatory role of PACAP38 in details. First, we in20 fused PACAP38 intracere...
Disorders involving the orofacial area represent a major medical and social problem. They are a consequence of central nociceptive processes associated with stimulation of the trigeminal nerve nucleus. A rat model of trigeminal pain, utilizing tongue jerks evoked by electrical tooth pulp stimulation during perfusion of the cerebral ventricles with various neuropeptide solutions, can be used in ...
A sheet of choroid plexus epithelial cells extends into each cerebral ventricle and secretes signaling factors into the CSF. To evaluate whether differences in the CSF proteome across ventricles arise, in part, from regional differences in choroid plexus gene expression, we defined the transcriptome of lateral ventricle (telencephalic) versus fourth ventricle (hindbrain) choroid plexus. We find...
BACKGROUND AND PURPOSE Clinical data suggest that Alzheimer disease (AD) and stroke together potentiate cognitive impairment. Inflammatory mechanisms are involved in AD pathology and stroke and may be the mediator between AD and stroke toxicity. METHODS AD was modeled by cerebroventricular injections of beta-amyloid (Abeta[25-35]) and subcortical lacunar infarcts by striatal endothelin inject...
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