This paper presents a novel research model – Contextual Constructs Model (CCM) and the theory that underpins it – Contextual Constructs Theory (CCT). First developed as part of a complex project investigating user perceptions of information quality during Web-based information retrieval, the CCM is not a single research method per se, but is a modelled research framework providing an over-archi...

Eukaryotic ectotherms of the Southern Ocean face energetic challenges to protein folding assisted by the cytosolic chaperonin CCT. We hypothesize that CCT and its client proteins (CPs) have co-evolved molecular adaptations that facilitate CCT-CP interaction and the ATP-driven folding cycle at low temperature. To test this hypothesis, we compared the functional and structural properties of CCT-C...

PURPOSE To measure the mean cerebral circulation time (CCT) in patients with symptomatic vasospasm stemming from subarachnoid hemorrhage and to determine any change after papaverine treatment. METHODS We studied 27 patients who received intraarterial papaverine from November 1992 to August 1995 to determine the CCT in 59 carotid territories. CCT was measured from the first image in which cont...

PURPOSE We investigated the distribution of central corneal thickness (CCT), and its association with age, sex, intraocular pressure (IOP), anterior chamber depth (ACD), axial length (AL), and the presence of systemic hypertension and diabetes in a Korean population. METHODS Our study is a population-based glaucoma prevalence study of residents aged ≥40 years in Namil-meon area, located in ce...

BACKGROUND Estimates of intraocular pressure (IOP) are influenced directly by the central corneal thickness (CCT). We assume and apply a single value for CCT (520 μm) in applanation tonometry estimates, although there is compelling evidence that CCT varies between individuals. OBJECTIVE To determine the influence of CCT and other factors on IOP among Ethiopians. METHODS A cross sectional st...

We examined the effect of lipoprotein deprivation on the expression of the rate-regulatory enzyme involved in phosphatidylcholine (PtdCho) synthesis, phosphocholine cytidylyltransferase (CCT), within an alveolar type II epithelial cell line (MLE-12). Compared with cells exposed to 10% fetal bovine serum (FBS, control), cells cultured with lipoprotein-deficient serum (LPDS) for 72 h had a 150% i...

Marketplace cultures, one of the main theoretical frameworks within consumer culture theory (CCT), offers grounds for study interactions with marketplace. One kind interaction occurs inside consumption communities. Most communities nowadays are online. Consumers go online to get information and advice from peers on their options processes. They participate in forums connect like-minded individu...

PURPOSE To investigate the repeatability and reproducibility of intraocular pressure (IOP) and central corneal thickness (CCT) measurements using a noncontact tono/pachymeter (NT-530P) and to assess the correlation of CCT with IOP. METHODS Forty-six eyes of healthy volunteers were measured by two examiners. Three consecutive measurements per eye were performed. Repeatability was assessed usin...

Purpose: Comparison of the effect of selective laser trabeculoplasty (SLT) in glaucoma patients with high and low central corneal thickness (CCT). Materials and methods: Clinical trial on 72 glaucoma patients, controlled on medication that received SLT as replacement therapy. We compared the effect of SLT on patients with CCT ≥ 550 μm with patients having CCT <550 μm. Primary end point was intr...