In recent years, the incidence of portal vein thrombosis (PVT) in patients with cirrhosis has increased; ranges from asymptomatic partial to complete occlusion. Treatment is difficult. Anticoagulation therapy may be optimal first-line treatment for acute PVT who lack variceal bleeding or mesenteric ischemia. Minimally invasive options include mechanical thrombectomy, chemical thrombolysis, and ...

Intracerebral microdialysis (MD) was applied in patients with subarachnoid hemorrhage. The regional CBF, the CMRO2, and oxygen extraction ratio (OER) were measured with simultaneous positron emission tomography (PET). The aim was to directly correlate alterations in dialysate levels of energy-related metabolites (lactate, lactate/pyruvate ratio, hypoxanthine) and excitatory amino acids (EAAs) (...

objective(s):biochemical markers are important for the timely diagnosis and follow-up of ischemic events. most of the markers have been previously studied in the context of cardiac ischemia. however, research on markers of non-cardiac events has been insufficient. therefore, we investigated the relationship between troponin and myoglobin which are commonly used markers of cardiac ischemia, in n...

objective(s): in the present study, we investigated the effect of ischemic preconditioning (ipc) on c-myb immunoreactivity as well as neuronal damage/death after a subsequent lethal transient ischemia in gerbils. materials and methods: ipc was subjected to a 2 min sublethal ischemia and a lethal transient ischemia was given 5 min transient ischemia. the animals in all of the groups were given r...

Objective(s): In the present study, we investigated the effect of ischemic preconditioning (IPC) on c-myb immunoreactivity as well as neuronal damage/death after a subsequent lethal transient ischemia in gerbils. Materials and Methods: IPC was subjected to a 2 min sublethal ischemia and a lethal transient ischemia was given 5 min transient ischemia. The animals in all of the groups were given ...

A MAJOR CONSIDERATION in the evaluation of experimental models of ischemic stroke in animals is the clinical relevance of the models. Difficulties arise in relating studies of models of focal cerebral ischemia to the clinical situations of strokes in humans because of many factors, including species differences, the effects of anesthesia, and the progressive nature of atherosclerosis. However, ...

introduction: ischemia leads to loss of neurons by apoptosis in specific brain regions, especially in the hippocampus. the purpose of this study was investigating the effects of exercise preconditioning on expression of bax, bcl-2, and caspase-3 proteins in hippocampal ca1 neurons after induction of cerebral ischemia. methods: male rats weighing 260-300 g were randomly allocated into three grou...

Ocotillol-type saponins are one kind of tetracyclic triterpenoids, sharing a tetrahydrofuran ring. Natural ocotillol-type saponins have been discovered in Panax quinquefolius L., Panax japonicus, Hana mina, and Vietnamese ginseng. In recent years, the semisynthesis of 20(S/R)-ocotillol-type saponins has been reported. The biological activities of ocotillol-type saponins include neuroprotective ...