نتایج جستجو برای: chewable tablet
تعداد نتایج: 32928 فیلتر نتایج به سال:
BACKGROUND Raltegravir is an HIV-1 integrase inhibitor approved for use in adults, children and infants ≥4 weeks of age. As alternatives to the original film-coated tablet, a chewable ethylcellulose (EC) tablet and oral granules for suspension (GFS) have been developed for use in children. The purpose of this study was to evaluate these formulations in adults prior to use in paediatric studies....
In recent years, scientists around the world are paying attention to the role of leukotrienes in the pathogenesis of bronchial asthma and allergic rhinitis. Leukotrienes – a group of biologically active substances produced from the metabolism of arachidonic acid. Increasing concentrations in the blood cause bronchoconstriction, increased bronchial secretion glands, increased vascular permeabili...
BACKGROUND Pediatric fixed-dose combinations (FDCs) are needed to facilitate antiretroviral therapy in children. We evaluated the relative bioavailability, safety, and therapeutic adequacy of a novel chewable pediatric FDC tablet of stavudine (7 mg), lamivudine (30 mg), and nevirapine (50 mg), referred to as GPO-VIR S7, and compared it with the individual original brand-name liquid formulations...
In this study, the resources of traditional Chinese medicine were exploited reasonably, which was mainly composed active components malus hupehensis and four kinds plant components, such as Pueraria lobata, tangerine peel, jujube corn sweet core. The preparation process product has been solved, preliminary efficacy experiments have carried out, proved to be able relieve symptoms alcohol discomf...
The aim of the present study was the formulation of a novel chewable tablet containing the non-steroidal anti-inflammatory bumadizone calcium (BZ) to deliver the drug to the colon for the local treatment of ulcerative colitis. Colon targeted granules were prepared following 32 full factorial design. The effect of two independent variables, namely, polymer type (Eudragit ® S100, Eudragit ® L100,...
BACKGROUND There is an unmet clinical need for a cat-specific formulation of amlodipine to treat hypertensive cats. OBJECTIVES To assess the efficacy of chewable amlodipine tablets in reducing systolic blood pressure (SBP) in cats diagnosed with systemic arterial hypertension. ANIMALS Seventy-seven client-owned cats with systemic hypertension were included (median age 14 years). METHODS T...
Kiwifruit are a rich source of vitamin C and also contain numerous phytochemicals, such as flavonoids, which may influence the bioavailability of kiwifruit-derived vitamin C. The aim of this study was to compare the relative bioavailability of synthetic versus kiwifruit-derived vitamin C using a randomised cross-over pharmacokinetic study design. Nine non-smoking males (aged 18-35 years) receiv...
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