Liquid methanol and methanol clusters have been comprehensively studied to reveal their local structure and hydrogen bond networks. However, our understanding of the crystal forms of methanol is rather limited. The known crystal structures of solid methanol, α, β, and γ, are composed of infinite hydrogen bond chains in their unit cell. The structural diversity of solid methanol is much less tha...

A near-infrared fluorescent probe (Cy-O-CHO) for the detection of endogenous Cys/Hcy in living cells was designed and synthesized. Cy-O-CHO exhibited high sensitivity and good selectivity to Cys/Hcy under physiological conditions with a detection limit of 7.9 nM for Cys.

In the present paper, we obtain some interesting properties for mero-morphic analytic functions related to Cho-Kwon-Srivastava Operator defined by means of an operator recently given by Ghanim and Darus.

The mutagenicity and cytotoxicity of five antitumor compounds (ellipticines) were investigated in the Chinese hamster ovary cell hypoxanthine-guanine phosphoribosyltransferase assay and in six strains of Salmonella. All five compounds (ellipticine, 9-methoxyellipticine, 9-hydroxyellipticine, 9-aminoellipticine, and 2-methyl-9-hydroxyellipticinium) were cytotoxic and mutagenic in the Chinese ham...

The cytotoxic action of 5-(3,3-dimethyll-triazeno)imidazole-4-carboxamide in Chinese hamster ovary cells is enhanced considerably in the presence oflight, when 5-diazoimidazole-4-carboxamide is being continu ously generated. A broad shoulder threshold-type survival curve is seen when the cells are exposed to 5-(3,3-dimethyll-triazeno)imidazole-4-carboxamide (both in light anddark). The drug had...

Cover (and back side), Alexa488-APEC staining (green) of the adenosine A 2A receptor in living Chinese hamster ovary cell transiently transfected with pcDNA3 A 2A R as well as pAS β-arrestin2-RFP (red).

Chinese hamster ovary (CHO) cell culture systems are the most widely used platform for industrial production of monoclonal antibodies (mAbs). The optimisation manufacturing conditions these high-value products is largely conducted off-line with little or no monitoring mAb quality in-process. Here, we propose DigiGlyc, a hybrid model that predicts critical attribute galactosylation. Having shown...

Introduction: Genital system is important herd in animal's creation. It is necessary for animal reproduction. Mammal has two sex in genital system such as male and female in separated animals. Animal reproduction destroyed by disorder of genital system. In this case, animals cannot produce an animal similar to them. Finally it cause overthrow a species of animals. Methods: Histomorpholog...

Three mammalian cell lines were examined for their ability to metabolize the regulatory oxysterol, 25-hydroxycholesterol, and derepress 3-hydroxy-3-methylglutaryl CoA reductase. In mouse L cell fibroblasts reductase activity was restored with the concomitant metabolism of 25-hydroxycholesterol via side-chain hydroxylation and scission of the C20-C22 bond. Chinese hamster lung cells did not appe...