نتایج جستجو برای: chitosan hydrogels

تعداد نتایج: 27111  

2015
Vanessa Zamora-Mora Carmen Mijangos

Composite ferrogels were obtained by encapsulation of magnetic nanoparticles at two different concentrations (2.0 and 5.0 % w/v) within mixed agarose/chitosan hydrogels having different concentrations of agarose (1.0, 1.5 and 2.0% (w/v)) and a fixed concentration of chitosan (0.5% (w/v)). The morphological characterization carried out by scanning electron microscopy showed that dried composite ...

Journal: :Biomaterials 2006
Peter Roughley Caroline Hoemann Eric DesRosiers Fackson Mwale John Antoniou Mauro Alini

The suitability of chitosan-based hydrogels as scaffolds for the encapsulation of intervertebral disc (IVD) cells and the accumulation of a functional extracellular matrix mimicking that of the nucleus pulposus (NP) was investigated. The specific hypothesis under study was that the cationic chitosan would form an ideal environment in which large quantities of newly synthesized anionic proteogly...

Introduction: Mathematical modeling of drug release is one of the ways to improve the rate of drug diffusion and infiltration in swollen hydrogel based systems. Using this method can provide a better understanding of the mechanisms of drug control and its release. Hydrogels are a swollen biomaterial that needs to be controlled for use in drug release. Purpose and methodology: In this study, fiv...

Journal: :Dalton transactions 2011
Natasha H Munro David W Green Ashley Dangerfield Kathryn M McGrath

Chitosan hydrogels are of considerable interest in synthetic biomimetic mineralisation strategies due to their favourable characteristics such as the presentation of a large surface area for crystal nucleation within a structured yet responsive scaffold. Chitosan hydrogels were prepared and subsequently calcium carbonate mineralisation was initiated using a method which combines alternate soaki...

2014
Christopher A. McKay Rebecca D. Pomrenke Joshua S. McLane Nicholas J. Schaub Elise K. DeSimone Lee A. Ligon Ryan J. Gilbert

Immediately following spinal cord injury, further injury can occur through several secondary injury cascades. As a consequence of cell lysis, an increase in extracellular Ca(2+) results in additional neuronal loss by inducing apoptosis. Thus, hydrogels that reduce extracellular Ca(2+) concentration may reduce secondary injury severity. The goal of this study was to develop composite hydrogels c...

2012
Nadia Ahmed Mohamed Mona Mohamed Fahmy

Four novel hydrogels based on chitosan were synthesized via a cross-linking reaction of chitosan with different concentrations of oxalyl bis 4-(2,5-dioxo-2H-pyrrol- 1(5H)-yl)benzamide. Their structures were confirmed by fourier transform infrared X-ray (FTIR), scanning electron microscopy (SEM) and X-ray diffraction. The antimicrobial activities of the hydrogels against two crop-threatening pat...

Journal: :Tissue engineering. Part A 2014
Seokwon Pok Omar M Benavides Patrick Hallal Jeffrey G Jacot

A novel cardiac scaffold comprised of decellularized porcine heart matrix was investigated for use as a biodegradable patch with a potential for surgical reconstruction of the right ventricular outflow tract. Powdered heart matrix solution was blended with chitosan and lyophilized to form three-dimensional scaffolds. For this investigation, we examined the influence of different blending ratios...

2014
Victoria Tamara Perchyonok Vanessa Reher Shengmiao Zhang Sias R. Grobler Theunis G. Oberholzer Ward Massey

Restorative materials in the new era aim to be “bioactive” and long-lasting. It has been suggested that the anti-inflammatory activity of some non-steroidal anti-inflammatory drugs (NSAIDs) may be partly due to their ability to scavenge reactive oxygen species (ROS) and reactive nitrogen species (RNS), as well as to inhibit the respiratory burst of neutrophils triggered by various activating ag...

Journal: :Journal of biomedical materials research. Part B, Applied biomaterials 2007
Yoon Yeo Wenliang Geng Taichi Ito Daniel S Kohane Jason A Burdick Milica Radisic

Conventional treatment options for myocardial infarction are limited by the inability of mature myocardium to regenerate after injury. Although functional improvements after injection of cells and growth factors have been demonstrated, the clinical utility of this procedure has been hampered by poor cell localization, low survival, and rapid clearance of injected growth factors. The main object...

Journal: :Molecules 2016
Huda E Abdelwahab Seham Y Hassan Mohamed A Mostafa Mohamed M El Sadek

Chitosan was reacted with four concentrations (2.5, 5, 10 and 20 mmol) of glutamic acid resulting in four types of glutamic-chitosan hydrogels (GCs), the activity of the resulted compounds on the removal of copper(II) and nickel(II) from wastewater were tested. The results indicated that by increasing glutamic acid concentration from GCs-1 to GCs-4, the efficiency of removing Cu(II) and Ni(II) ...

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