PURPOSE To determine the sensitivity, specificity, and field utility of the Cepheid GeneXpert Chlamydia trachomatis (CT) Assay (GeneXpert) for ocular chlamydia infection compared to Roche Amplicor CT assay (Amplicor). METHODS In a trachoma-endemic community in Kongwa Tanzania, 144 children ages 0 to 9 were surveyed to assess clinical trachoma and had two ocular swabs taken. One swab was proce...

OBJECTIVE The objective of this study was to observe pregnancy outcomes in mice infected transvaginally with Chlamydia trachomatis. METHODS Pregnant mice were inoculated transvaginally with either C. trachomatis (CT) or sterile calf serum (CON) on pregnancy day 4. Pregnancy outcomes as well as genital tract histology and culture were compared. Statistical analysis was performed using Fisher's...

BACKGROUND Chlamydia trachomatis and Neisseria gonorrhoeae are important bacterial pathogens of sexually transmitted infections (STIs) worldwide. This study sought to compare the analytical sensitivity and specificity of conventional methods against a rapid molecular method in detecting STIs caused by these bacteria. METHODS Ninety five first-time male attendees of the Genito-urinary Medicine...

OBJECTIVES This study assessed the performances of the Presto CT-NG assay, the Lightmix Kit 480 HT CT/NG and the COBAS Amplicor for Chlamydia trachomatis and Neisseria gonorrhoeae detection. DESIGN A cross-sectional study design. SETTING Izore, Centre for Diagnosing Infectious Diseases in Friesland, the Netherlands, tested samples sent from regional sexually transmitted infection (STI) outp...

Reports about the extragenital spread of Chlamydia trachomatis (CT) to oropharynx are limited. We report a male patient with progressive tonsillopharyngitis resistant to amoxicillin/clavulanic acid therapy. The patient presented 9 days after an orogenital and oroanal sexual intercourse with a female sex worker. The microimmunofluorescence revealed CT tonsillopharyngitis, and after completing a ...

Women living in rural areas of Amazonas - the riverine have difficulty accessing adequate health care, aggravating their vulnerability face various pathological processes, such as cervical cancer and sexually transmitted infections. Strategies that expand coverage screening early diagnosis are welcome. To evaluate prevalence Human Papillomavirus (HPV) Chlamydia trachomatis (CT) riverside women ...

patients and methods in the current descriptive study, 255 endocervical swab samples were collected from the obstetrics and gynecology clinics of kashan, iran from december 2012 to july 2013. cervical swabs were placed in transport media and sent to the laboratory. to identify c. trachomatis in the samples polymerase chain reaction (pcr) was performed to amplify a sequence in the cryptic plasmi...

Objective Chlamydia trachomatis (CT) infection is the most common sexually transmitted disease in the world that can persist and also ascend in the genital tract. This intracellular and silent infection is related to some adverse pregnancy outcomes, such as miscarriage. The aims of this study were to explore the best CT screening tests using blood and vaginal samples and to investigate the corr...

chlamydia trachomatis infections are the most prevalent bacterial sexually transmitted infections (sti) recognized throughout the world. the aim of this study was to determine the prevalence of chlamydia trachomatis among a randomized statistical group of women suffering from cervicitis in tehran- iran. during a 12- month- period, jan 2003 to jan 2004, 142 endocervical samples were taken from w...