A bioassay of analytical-grade chlordane for possible carcinogenicity was conducted by administering the test material in feed to Osborne-Mendel rats and B6C3F1 mice. Groups of 50 rats of each sex were administered low or high concentrations of the chlordane for 80 weeks, then observed for 29 weeks. Because of toxic effects, doses were reduced for both male and female rats during the course of ...

Virtual ly 32 years ago in the summer of 1B16 a small number of green ajid brown beetles were collected al Riverton, N . J. They were sent to the United States National Museum in Washington where taxonomic experts identified them as the Japanese beetle. I t was believed the insect made its accidental introduction into this country a year or two earl ier as grubs in soil around the roots of exot...

Persistent halogenated xenobiotics such as chlorinated cyclodienes are known to be subject to atmospheric longrange transports into Arctic and Antarctic regions [Arctic Monitoring and Assessment Programme (AMAP) 2004]. As a consequence, chlordane, a complex mixture of various chemically similar components, has been detected in biota of these remote areas. Among the major constituents of this mi...

Organochlorines and heavy metals have bioaccumulated in Arctic wildlife, which is an important food source for the Inuit. In this study, we have developed a statistical model to describe the population distribution of contaminant exposure and the usual intake of the high-end contaminant consumers. Monte Carlo methods are used to account for variations due to seasonal dietary pattern and contami...