a convenient liquid chromatographic-single quadrupole mass spectrometric (lc-ms) method was developed and validated for dexchlorpheniramine maleate (inn name: chlorphenamine) determination in human plasma. the need for just a single liquid-liquid extraction with ethyl acetate and being highly sensitive were the advantages of this method. the linearity was also excellent over the range of 1 to 1...

these authors considered K.F. to be an acceptable The Karl Fischer and a gas chromatographic method for final molasses. Errors due to atmospheric method of water determinations are described. These and fading end-points can be overcome by two methods are with the vacuum oven instrumental methods. and Kviesitis13 has shown that method for the measurement of water in final molasses. stable end-po...

Lipophilicity (logP) represents one of the most studied and most frequently used fundamental physicochemical properties. At present there are several possibilities for its quantitative expression and many of them stems from chromatographic experiments. Numerous attempts have been made to compare different computational methods, chromatographic methods vs. computational approaches, as well as ch...

A major challenge in metabolomics is achieving reproducible, robust chromatographic resolution with a single analytical LC/MS method for endogenous cellular metabolites, due to their diversity of chemical and physical properties. A more manageable chromatographic solution is to develop pathway-targeted analytical methods for smaller sets of metabolites. Building an optimized targeted LC/MS/MS m...

There has been an extensive discussion in the forensic toxicology community regarding the effect of trauma on the enzymatic method for ethanol analysis. There is a paucity of information in the literature that addresses this question. This study was designed to compare the Dade Behring Dimension enzymatic method with the reliable gas chromatographic method. The blood samples collected at the sa...