Chromoblastomycosis is a chronic fungal infection of the skin and subcutaneous tissue. The infection usually results from a traumatic injury and inoculation of microorganism from a specific group of dematiaceous fungi (usually Fonsecaea pedrosoi, Phialophora verrucosa, Cladophialophora carrionii). In the tissues fungi produce characteristic sclerotic cells or muriform cells. Dermal lesions can ...

Eumycetoma and chromoblastomycosis are chronic, disfiguring fungal infections of the subcutaneous tissue that rarely resolve spontaneously. Most patients do not achieve sustained long-term benefits from available treatments; therefore, new therapeutic options are needed. We evaluated the efficacy of posaconazole, a new extended-spectrum triazole antifungal agent, in 12 patients with eumycetoma ...

Chromomycosis or chromoblastomycosis is a chronic deep skin mycosis that affects the skin and subcutaneous tissue and is caused by fungi from the Dematiaceae family, which are imperfect fungi that produce pigments similar to melanin. Several species are known to cause chromoblastomycosis; all have low virulence and produce similar clinical manifestations. The most common species is Fonsecaea pe...

Chromomycosis or chromoblastomycosis is a chronic deep skin mycosis that affects the skin and subcutaneous tissue and is caused by fungi from the Dematiaceae family, which are imperfect fungi that produce pigments similar to melanin. Several species are known to cause chromoblastomycosis; all have low virulence and produce similar clinical manifestations. The most common species is Fonsecaea pe...

Chromoblastomycosis is one of the most frequent infections caused by melanized fungi. It is a subcutaneous fungal infection, usually an occupational related disease, mainly affecting individuals in tropical and temperate regions. Although several species are etiologic agents, Fonsecaea pedrosoi and Cladophialophora carrionii are prevalent in the endemic areas. Chromoblastomycosis lesions are po...

We report a case of chromoblastomycosis in lesions on the chest and foot. Itraconazole was chosen as the initial treatment for this patient, who was followed up for 8 months before becoming noncompliant. The pathogenic fungal species was identified as Rhinocladiella similis by ITS region sequencing. In vitro analyses indicate that the fungus was sensitive to posaconazole and itraconazole. This ...

A 71-year-old farmer from the Solomon Islands presented in Melbourne with fungating skin lesions on his left lower leg. The process began 20 years earlier, leaving areas of scarring between the active sites (Figure, A and B). He was otherwise well. A skin biopsy showed granulomatous inflammation with sclerotic bodies characteristic of chromoblastomycosis (Figure, C), and Fonsecaea pedrosoi was ...

Chromoblastomycosis (CM), a chronic subcutaneous mycosis, is caused by several dematiaceous fungi, the most common being Fonsecaea pedrosoi. It usually occurs in the lower extremities following traumatic implantation of the organisms. We are reporting a case of chromoblastomycosis on the right lower limb in a sporotrichoid pattern caused by F. pedrosoi. The pattern was probably due to lymphatic...

Chromoblastomycosis is a chronic fungal infection of the skin and subcutaneous tissue. It usually occurs following trauma with vegetative matter and mainly affects middle-aged male agricultural workers. Only a few cases have been reported in children. The lesions commonly involve the lower limbs, while the upper limbs and face are only rarely affected. We report a case of cutaneous chromoblasto...