Mental retardation is a common problem with major implications for a nation’s health, education and community services. The causes of mental retardation have been found to have a definite etiological basis, which may be biochemical, chromosomal, Mendelian genetic disorders, or due to environmental effects such as toxins, infections, trauma or perinatal anoxia. The underlying causes remain unkno...

the frequency of chromosomal aberrations was studied in the peripheral blood lymphocytes of 65 radiology technologists crt) working at hospitals chronically exposed to x-rays. although film dosimetry did not show the maximal annual permitted dose in any of the examined subjects, cytogenetic analysis detected fairly high levels of chromosomal aberrations in r t compared to unexposed controls. th...

background : aneuploidy is one of the main causes of congenital anomalies, mental and physical disabilities, in new-borns. the aim of this study was to determine various chromosomal aneuploidies in the first and second trimester screening of pregnant women, in iran. methods : a descriptive retrospective study was conducted on 125,170 pregnant women referred to a major referral medical diagnosti...

Background The present study offers our contribution on the topic by a retrospective analysis of the prevalence of chromosomal abnormalities in a population of Iranian infertile men attending assisted reproduction programs. MaterialsAndMethods Cytogenetic analysis was performed according to standard methods on cultured cells obtained from the patient peripheral blood. In all, 874 files belongin...

Several environmental pollutants can cause damage to chromosomes, one of which is the heavy metal NiNO3. Some plant extracts have antigenotoxic properties that result in a decrease chromosomal damage. Member flowering plants need be tested seagrass. One seagrass species Enhalus acoroides was found contain phytochemical compounds. This study aimed analyse genotoxic effect and potential encapsula...

objective: chromosomal aberrations are common causes of multiple anomaly syndromes. recurrent chromosomal aberrations have been identified by conventional cytogenetic methods used widely as one of the most important clinical diagnostic techniques. materials and methods: in this retrospective study, the incidences of chromosomal aberrations were evaluated in a six year period from 2005 to 2011 i...

The effects of commercial formulations Viburnum opulus and Equisetum arvense extract on anti-cytotoxicity anti-genotoxicity were evaluated at the root tip Allium cepa L. Distilled water (negative control), dimethyl sulfoxide (DMSO), ethyl methane sulfonate (EMS, positive 5% 10% doses V. E. extracts applied for 24 48 hours. Cytotoxicity genotoxicity by calculating %mitotic index %chromosomal abe...

Higher plants, an important material for genetic tests to monitor various pollutant present in the environment. Among the plant species, Alium cepa has been used to evaluate chromosome aberrations and disturbances in the mitotic cycle. Now days, it has been used to assess a great number of genotoxic/antigenotoxic agents, which contributes to its increasing application in environmental monitorin...

Non Hodgkin’s Lymphoma (NHL) or Lymphoma is a cancer that affects the lymphocytes of the immune system and present as a solid of lymphoid cell mass. Genetic disorder is one of the important factors for development NHL .The present study of bone marrow sample includes 65 NHL patients (46 male and 19 female) Chromosome analysis demonstrated that about 73.84 % of metaphase plate of NHL patients sh...