PURPOSE To better define cytogenetic mechanisms of CDKN2 loss at 9p21 and of DBCCR1 loss at 9q33 in bladder cancer, and to determine correlation with p53 and pRb. EXPERIMENTAL DESIGN Two-color fluorescence in situ hybridization (FISH) using a chromosome 9 centromeric probe and locus-specific probes was performed. p53 and pRb were assessed by immunohistochemistry. RESULTS Thirty-seven of fif...

In this study, the karyotypic characteristics of Chondrostoma regium (Heckel, 1843) have been investigated. Fish samples were caught from Karasu River (Euphrates Basin) with fishing net. The live fish transported to laboratory and kept in aerated aquaria before analyses. karyotype analysis was performed kidney gill epithelium cells. It determined that C. had 2n=50 chromosomes. detail, formula a...

human chromosomes in amnion cells and lymphocytes with normal karyotype and in lymphocytes with pathological karyotype (2n=47, +21) were compared as to their position in the metaphase. none of the collectives showed sex differences. measurement of the radial distances revealed more peripheral position of the majority of large chromosomes. the satellite-carrying chromosomes of the d group always...

A patient with Turner phenotype was found to carry two de novo chromosome aberrations: a 45,X line and a whole arm reciprocal translocation t(3;9). Fluorescence in situ hybridisation on metaphase cells using alpha satellite DNA for chromosome 3 and beta satellite and 'classical' satellite DNA for chromosome 9 showed that the centromeric region of chromosome 3 was retained in the 3q9q translocat...