Introduction: Diabetes mellitus is the most common endocrine disorder with increasing incidence. 30% of diabetic persons have some type of mucocutaneous involvement from trivial to life threatening during the course of their chronic disease. Aims Of The Study:To study the prevalence of mucocutaneous manifestations in Diabetes mellitus in our locality and to analyse the histopathological spectru...

On examination, he had white adherent plaques of thrush and angular cheilitis [Figures 1A and 1B]. His nails were markedly thickened, fragmented, and discolored [Figure 2A]. He also had skin lesions characterized by erythematous, hyperkeratotic, serpiginous plaques over arms [Figure 2B] and scarring alopecia. His investigations revealed hemoglobin of 14.4 gm%, total WBC count 7800cells/mm and d...

Chronic mucocutaneous candidiasis (CMC) refers to a group of disorders which have in common recurrent and persistent infections of the skin, nails and mucous membranes by Candida albicans and occasionally other candida species. A proportion of these patients show an associated endocrinopathy as part of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) syndrome. Many ca...

We present a case of chronic mucocutaneous candidiasis of the chronic diffuse kind. It began at eight months of age with lesions in plaque in the totality of the oral and nasal mucosa with affection of the nails. He received different treatment during ten years, without improvements. The diagnosis was established by clinical features en laboratory exams as follows: Skin test to Candida antigen ...

Chronic mucocutaneous candidiasis is a rare disorder characterized by persistent and recurrent infections by Candida due to changes in cellular immunity and may be associated with autoimmune endocrine disorders. It is refractory to the usual antifungal treatments, which merely control it with imidazole derivatives. This reports the case of a 50-year-old female patient who referred vaginal disch...