2. Chronic Periodontitis is highly prevalent in the adult population and is found in approximately 47% of adults in the U.S. (Eke et al., 2012). Chronic periodontitis is the most common form of periodontitis throughout the world. It should be noted that there are some uncommon forms of periodontitis, grouped together under the name “Aggressive Periodontitis” that are characterized by severe des...

Background: Chronic periodontitis causes systemic inflammation and increases C-reactive protein (CRP). CRP has been implicated as a possible mediator of associating periodontitis and several systemic diseases. The aim of the present study was to investigate systemic levels of CRP in patients with chronic periodontitis in comparison to periodontally healthy individuals.    Materials and methods:...

The acute phase of chronic periodontitis may occur even in patients during supportive periodontal therapy. However, the details are not fully understood. Since the natural environment, including meteorology affects human health, we hypothesized that weather conditions may affect occurrence of acute phase of chronic periodontitis. The aim of this study was to investigate the relationship between...

Periodontitis is a highly prevalent, biofilm-mediated chronic inflammatory disease that results in the loss of the tooth-supporting tissues. It features two major clinical entities: chronic periodontitis, which is more common, and aggressive periodontitis, which usually has an early onset and a rapid progression. Natural killer (NK) cells are a distinct subgroup of lymphocytes that play a major...

background the association between tumor necrosis factor-alpha (tnf-α) (-308 g/a) gene polymorphisms and level of tissue destruction and periodontal disease progression is not proved. objectives the present study investigated the stereological parameters of interdental papilla in chronic periodontitis (cp) patients with tnf-α (-308 g/a) gene polymorphisms. materials and methods sixty gingiva sa...

Background and Aim: Considering the critical role of inflammatory responses in periodontal disease, knowledge about the immune system and cytokines seems nec-essary. The aim of this study was to evaluate the level of IL-23 and IL-17 in gingival crevicular fluid (GCF) of patients with chronic and aggressive periodontitis, before and after non-surgical periodontal therapy. Materials and Methods:...

BACKGROUND There is a strong evidence that genetic as well as environmental factors affect the age of onset, severity and lifetime risk of developing periodontitis. The objective of the present study was to compare and to evaluate the association between interleukin (IL)-1α(-889) and gene polymorphisms in patients with generalized aggressive periodontitis, chronic periodontitis and healthy cont...