The Majority of the long stay psychiatric patients who are in need of rehabilitation suffer from schizophrenia. Most of them enter the old age with this illness, and besides the consequences of schizophrenia, they are facing the deprivation and misery due to the old age. In contrast to the previous decades in which there was no effective treatment for schizophrenia, today with the immediate dia...

traditionally, schizophrenia was considered to be a severe psychiatric disorder, with a chronic course and an unfavorable outcome. throughout history, there has been incidence of schizophrenia, roughly one percent of the population, consistently, in every culture. it is generally acknowledged that schizophrenia has multifactorial etiology, with multiple susceptibility genes interacting with env...

abstract aim and background: theory of mind is the ability to attribute one’s own or others mental states which has an important role in social and behavioral performances. the purpose of the present study was compare theory of mind in patients with schizophrenia and major depression with normal individuals. methods and materials: the present research was a causal- comparative study. the subjec...

OBJECTIVE This overview focuses on neurobiological abnormalities found in subjects with schizotypal personality disorder, the prototype of the schizophrenia spectrum disorders, and chronic schizophrenia in the context of common vulnerabilities shared by schizotypal personality disorder and schizophrenia, as well as the factors that protect against the severe cognitive/social deficits and frank ...

Introduction: Schizophrenia is a chronic mental illness, whose aetiology is still unclear; therefore, information about differences in serum protein patterns may improve the understanding of the pathophysiology of schizophrenia. The goal of this study was to use the proteomic approach to identify altered protein levels in the serum samples from patients with schizophrenia. Methods: Blood wa...

Background: Schizophrenia is a psychiatric disorder that impairs several intellectual functions, including attention processes.  Objectives: To investigate attention deficit in a group of patients with schizophrenia.  Method: Thirty patients with schizophrenia hospitalized in three psychiatric wards in Shiraz and Isfahan and 30 normal healthy subjects matched for age, gender and years of educat...

screening is one of the ways to combat tuberculosis (tb) and should be mostly concentrated on groups showing some symptoms of the disease. tuberculosis can be transferred from person to person in laboratories, prisons and psychiatry hospitals. the purpose of this study was to survey pulmonary tb in patients with schizophrenia in rasht.in this descriptive-cross sectional, two hundred fifty seven...

Background Chronic schizophrenia is significantly influenced by negative symptoms, with several known contributors to secondary symptoms. However, the impact of these factors and symptoms on social functioning warrants further exploration. Methods We assessed clinical antipsychotic adverse reactions, 283 hospitalized patients chronic using various standardized interviews scales. conducted multi...

A progressive post-onset decrease in gray matter volume 1.5 years after first hospitalization in schizophrenia has been shown in superior temporal gyrus (STG). However, it is still controversial whether progressive volume reduction occurs in chronic schizophrenia in the STG and amygdala-hippocampal complex (AHC), structures found to be abnormal in chronic schizophrenia. These structures were me...

The aim of this study was to detect the mRNA expression levels of the dopamine D2 receptor (DRD2) and dopamine transporter (DAT) in peripheral blood leukocytes (PBLs) of schizophrenia patients and to explore the relationship between the mRNA expression levels and the clinical symptoms of schizophrenia. The research included 25 cases of acute schizophrenia patients, 27 cases of chronic schizophr...