Integrons capture gene cassettes by using a site-specific recombination mechanism. As only one class of integron and integron-determined site-specific recombination system has been studied in detail, the properties of a second class, the only known class 3 integron, were examined. The configuration of the three potentially definitive features of integrons, the intI3 gene, the adjacent attI3 rec...

conclusions the study revealed a high prevalence of multi-drug resistance (mdr), class 1 integron, sccmec type iii, and spa type t030 amongst mrsa associated with burn wounds in an iranian hospital. the existence of sccmec type iii in burn patients emphasizes the nosocomial origin of these strains. objectives the aim of this study was to determine the distribution and molecular types of mrsa in...

The presence of integrons in 85 multiresistant German isolates of the predominating Salmonella enterica subsp. enterica serovar Paratyphi B dT(+) clone was investigated. All isolates possessed a chromosomally located Tn7-like class 2 integron carrying the same dfrA1-sat1-aadA1 array of gene cassettes. Only four isolates (4.7%) revealed an additional class 1 integron with two strains each contai...

background and objectives: pseudomonas aeruginosa is one of the most important causative agents of nosocomial infections especially in icu and burn units. p. aeruginosa infections are normally difficult to eradicate due to acquired resistance to many antibiotics. recent appearance of carbapenem resistant p. aeruginosa isolates is considered a major healthcare problem. the present study was cond...

BACKGROUND Emergence and global dissemination of multiresistant strains of enteric pathogens is a very concerning problem from both epidemiological and Public Health points of view. Shigella sonnei is the serogroup of Shigella most frequently responsible for sporadic and epidemic enteritis in developed countries. The dissemination is associated most often to human to human transmission, but foo...

Pseudomonas aeruginosa is an opportunistic human pathogen that causes nosocomial infections. This bacterium is characterized by inherent resistance to a wide variety of antimicrobials; the inherent resistance is always mediated by antibiotic resistance genes (3, 10). A genetic element, the integron, is potentially a major agent in the dissemination of multidrug resistance among gram-negative ba...

objective(s): drug resistant acinetobacter baumannii have emerged as a major problem in many hospitals and intensive care units. various types of extended spectrum beta-lactamases (esbls) are responsible for resistance to beta- lactam antibiotics in different parts of the world. the objective of this study was to determine the prevalence of integron class1 (int 1) and esbl types per-1, per-2 an...

BACKGROUND Multidrug-resistant (MDR) Acinetobacter spp. acquire antimicrobial agent-resistance genes via class 1 integrons. In this study, integrons were characterized to investigate the antimicrobial resistance mechanisms of MDR Acinetobacter isolates. In addition, the relationship between the integron type and integron-harboring bacterial species was analyzed by using epidemiological typing m...

During a β-lactam resistance surveillance study, 12 IMP-18-positive Pseudomonas aeruginosa isolates belonging to 9 different pulsed-field gel electrophoresis groups were identified. In nine isolates, a class I integron with a novel gene array was identified that contained bla(IMP-18) and bla(OXA-224), while in two isolates the class I integron contained bla(IMP-18) and bla(OXA-2) but in a new a...

OBJECTIVES To investigate the diversity of integrons and extended-spectrum beta-lactamases (ESBLs) among Enterobacteriaceae from chickens and swine in Portugal and analyse the clonal relationships between Portuguese ESBL-producing isolates of animal and human origin. METHODS We analysed samples from faeces of healthy swine (HSF, n = 35), from uncooked chicken carcasses (CM, n = 20) and from f...