background the immune system plays important roles in determining the outcomes of hepatitis c virus (hcv) infection. interleukin-23 and -27 (il-23 and il-27) are two novel il-12 cytokine family members known to enhance the t-lymphocyte response, but their precise involvement in hcv infection is not well known. objectives we investigated the serum il-27 and il-23 levels in patients with hcv infe...

conclusions this study showed that ifnβ-1a decreased oxidant impacts in ms patients, but had no influence in improving mitochondrial dysfunction. results in the patients group (30 patients), a significant difference was observed in their measured biochemical factors in comparison to the control group (p = 0.001), however, after six months of using ifnβ-1a, only mda was shown in the main (p = 0....

Background: It is now well established that several environmental stress factors cause activation of p38 MAP kinase and JNK in various cell types to produce chemokines. Objective: To investigate the expression of CXC chemokines Gro/KC and SDF- 1a in rat's H4 hepatoma cells in response to heat shock, hyperosmolarity and oxidative stress. Methods: Hepatoma cells were maintained in MEM medium. Cel...