An increase in mucocutaneous leishmaniasis (ML) cases in northern (Brazil) motivated this study. In 44 ML patients with clinical diagnosis, only 13 parasitologically confirmed cases exhibited mucosal lesion suggestive of ML. Other conditions involving nasal manifestations are frequently confounded with ML. Therefore, otorhinolaryngologic examination is important in the clinical management of ML.

The prevalence of migraine in the general population has been calculated using a standard mailed questionnaire, which inquired about headache and the individual features of migraine, and which previously had been compared with a clinical diagnosis. In three separate epidemiological surveys the prevalence in the preceding year was found to be between 23 and 29% in women and between 15 and 20% in...

Primary (isolated) tuberculosis of the appendix is a clinical rarity, its reported incidence being 0.1 to 0.3%. Diagnosis is often made only after histopathological examination of resected specimen. This report describes two patients with clinical diagnosis of acute appendicitis and appendicular mass respectively, who were finally diagnosed to have tuberculosis of the appendix on histopathologi...

This study consisted of an analysis of autopsy material from 3,824 persons who were 30 years of age or older in whom the arterial circle of Willis was scored for the severity and extent of atherosclerosis. Several criteria were used for hypertension. These consisted of the heart weight, the clinical diagnosis of hypertension, and the blood pressure. Regardless of which criterion was used, a def...

INTRODUCTION Tiredness is a common presentation in general practice for which pathology tests are commonly ordered. Our aim was to study their utilisation for tiredness. METHODS We examined an integrated database which contains the medical records for 58,139 patients and their 696,518 associated general practitioner encounters. Three hundred and forty-two patients and their 1652 associated en...

Day-to-day functioning is a component of health-related quality of life and is an important end point for therapies to treat Huntington Disease (HD). Specific areas of day-to-day function changes have not been reported for prodromal or very early stages of HD. An exploratory self-report telephone interview was conducted with sixteen people with prodromal HD or early HD who met criteria designed...

The use of software in medical devices and their accessories has led to significant improvements in clinical diagnosis and treatment of a vast range of illnesses. However, to benefit patients and users, device-related software must be properly developed and tested before use. This article discusses a United States guidance document that describes the type of documentation needed to show that th...

Modern oncology is a rapidly growing area in medicine. Cancer is a disease diagnosed on the basis of cellular changes hence objectivity takes the lead. Clinical observation, detailed examination and some feasibility studies were conducted in Ayurvedic methods to understand and identify cancer systematically. Abdominal presentation as tumour is discussed since it is one of the major area for cli...