introduction: epidermal growth factor receptor (egfr) has been shown to play a critical role in tumor cell growth and its overexpression has been observed in many epithelial tumors. in the field of cancer vaccine research, displaying the peptide mimotope on the surface of phage particles has shown promising results. methods: in this study using m13-pviii phage display system, two constructs wer...

To the Editor, As health care sector accounts for approximately 5% of global greenhouse-gases (GHG) emissions, several systems are calling adoption transparent and standardized metrics GHG accounting, paving way towards net zero healthcare.1 Although allergen immunotherapy (AIT) has been proposed as a prototype individualized medicine in terms clinical response safety allergic disease, commutin...

Immunotherapy has been used for years in many types of cancer therapy. Recently, cancer immunotherapy has focused on mechanisms which can enhance the development of cell-mediated immunity. Anticancer medications are administered to inhibit immunosuppressive factors such as nagalase enzyme, which is produced by neoplastic cells and destroys macrophage activating factor (Gc-MAF). Anti-neoplastics...

these are notes from introductory survey lectures given at the institute for studies in theoretical physics and mathematics (ipm), teheran, in 2008 and 2010. we present the definition and the fundamental properties of fomin-zelevinsky’s cluster algebras. then, we introduce quiver representations and show how they can be used to construct cluster variables, which are the canonical generators of ...

Breast cancer, as a heterogeneous disease, includes a wide range of pathological and clinical behaviors. Current treatment protocols, including radiotherapy, chemotherapy, and hormone replacement therapy, are mainly associated with poor response and high rate of recurrence. Therefore, more efforts are needed to develop alternative therapies for this type of cancer. Immunotherapy, as a novel str...

allergen immunotherapy involves the administration of gradually increasing quantities of specific allergens to patients with ige-mediated conditions until a dose is reached that is effective in reducing disease severity from natural exposure. in the present study we evaluated a period of six years immunotherapy allergic rhinitis and allergic asthma patients with positive skin prick test of comm...

brucellosis is an infectious disease and it seems that it affects human immune system and can cause acute, subacute and chronic clinical features. forty patients suffering from chronic brucellosis were studied for cd3+, cd4+,cd8+, cd19+, cells and cd4+/cd8+ ratio by flow cytometry before and after treatment with antibiotics and immunopotentiators. the results were compared with 15 healthy contr...

These are notes from introductory survey lectures given at the Institute for Studies in Theoretical Physics and Mathematics (IPM), Teheran, in 2008 and 2010. We present the definition and the fundamental properties of Fomin-Zelevinsky’s cluster algebras. Then, we introduce quiver representations and show how they can be used to construct cluster variables, which are the canonical generator...

specific local immunotherapy has been recently introduced as an alternative to classic subcutaneous immunotherapy in treatment of allergic rhinitis. in this study, the effects of sublingual immunotherapy (slit) on symptoms and medication score and skin prick test evaluation of patients with allergic rhinitis were investigated. in this placebo controlled trial, twenty four patients aged 5-18 yea...