BACKGROUND Bipolar electro-coagulation has a reported efficacy in treating epilepsy involving functional cortex by pure electro-coagulation or combination with resection. However, the mechanisms of bipolar electro-coagulation are not completely known. We studied the acute cortical blood flow and histological changes after bipolar electro-coagulation in 24 patients with intractable temporal lobe...

• For the past fift3 j-ears investigators have attempted to show a relationship between high lipid diets and the production of atherosclerosis and thrombosis. Recently interest has shifted from a consideration of diets in the pathogenesis of atherosclerosis to a study of their association with alterations in the levels of coagulation factors as a possible cause of thrombus formation, a possibil...

The process of haemostasis is complex and is further complicated in the parturient because of the physiological changes of pregnancy. Understanding these changes and the impact that they have on the safety profile of the anaesthetic options for labour and delivery is crucial to any anaesthetist caring for the parturient. This article analyses current theories on coagulation and reviews the phys...

Standard coagulation tests have a low specificity and sensitivity for diagnosing disseminated intravascular coagulation. The aim of this study was to determine whether whole blood thromboelastometry (TEM) detects lipopolysaccharide (LPS)-induced changes in coagulation. Blood samples from 10 pigs were drawn at baseline, before and at the end of LPS infusion and 2, 3, 4 and 5 h after the start of...

To analyze the predictive effect of thrombelastogram (TEG) in the changes of coagulation functions of patients with traumatic brain hemorrhage, as well as to provide a practice basis for clinical guidance. 54 cases were observed from Aug. 2013-Oct. 2014. All patients received a TEG test 1d, 3d and 7d after traumatic injury. According to the statistical analysis, the comparison among the aforeme...

Background Changes in the coagulation system in patients undergoing surgery for lung cancer have been sparsely investigated and the impact of the surgical trauma on the coagulation system is largely unknown in these patients. An increased knowledge could potentially improve the thromboprophylaxis regimes. The aim of this study was to assess the coagulation profile evoked in patients undergoing ...

introduction: the main inhibitors of coagulation pathway are antithrombin (at), protein c and protein s. these inhibitors are necessary to prevent thromboembolism. hereditary deficiency of inhibitors is the main cause of alteration in balance between the anti-clotting and the formation of thrombin. patients with this abnormality are susceptible to venous thromboembolism (vte). two major clinica...

BACKGROUND Gambling disorders affect about one percent of adults. Effective treatments are available but only a small proportion of affected individuals will choose to attend formal treatment. As a result, self-directed treatments have also been developed and found effective. Self-directed treatments provide individuals with information and support to initiate a recovery program without attendi...

background some of the dental procedures can cause bleeding. bleeding control can be difficult in some patients because of systemic disease or chronic anticoagulant therapy, so they may be at increased risk for bleeding occurrences or even death following invasive dental procedures. this study was schemed to measure the knowledge of general dentists in shiraz city regarding coagulation tests pe...