INTRODUCTION Arterial hypertension is a worldwide public health problem and one of the major risk factors for chronic kidney disease development. METHODS In order to compare the Cockcroft-Gault (CG) equation with serum creatinine and 24-hour creatinine clearance (CrCl) for the screening of reduced renal function, a cross-sectional study of 198 hypertensive patients was undertaken at a basic h...

OBJECTIVE In clinical trials of dabigatran and rivaroxaban for stroke prevention in atrial fibrillation (AF), drug eligibility and dosing were determined using the Cockcroft-Gault equation to estimate creatine clearance as a measure of renal function. This cross-sectional study aimed to compare whether using estimated glomerular filtration rate (eGFR) by the widely available and widely used Mod...

Glomerular filtration rate (GFR) is commonly assessed by measurement of endogenous creatinine clearance (Ccr). Several formulae have been described to calculate Ccr from plasma creatinine. I have evaluated the effectiveness of four formulae in 35 healthy subjects (21M and 14F, 18-34 years) and in 41 patients (24M, 17F, 20-69 years) attending a renal clinic with diminished renal function (serum ...

PURPOSE There are growing doubts about the accuracy of Cockcroft-Gault formula (CG) used for the estimation of creatinine clearance, especially in elderly. Recently, the authors of the multicenter trial of the Modification of Diet in Renal Diseases (MDRD) have proposed a new equation. Moreover, Baracskay et al. (B), proposed the special formula for the estimation of kidney function (KF) in elde...

OBJECTIVE To test the Mayo Clinic Quadratic (MCQ) equation against isotopic glomerular filtration rate, compared with the Modification of Diet in Renal Disease (MDRD) and the Cockcroft-Gault formulas, in type 2 diabetes. RESEARCH DESIGN AND METHODS Based on values obtained with iothalamate, 118 type 2 diabetic patients were divided into three groups according to renal function: hyperfiltratio...

BACKGROUND: The 4-variable Modification of Diet in Renal Disease (4-v MDRD) and Cockcroft-Gault (CG) equations are commonly used for estimating glomerular filtration rate (GFR); however, neither of these equations has been validated in an indigenous African population. The aim of this study was to evaluate the performance of the 4-v MDRD and CG equations for estimating GFR in black South Africa...

INTRODUCTION Individuals with glomerular filtration rate (GFR) ≥60 ml/min/1.73 m2 estimated by the Cockcroft-Gault formula (CG) who undergo percutaneous coronary intervention (PCI) frequently develop contrast-induced nephropathy (CIN). This study aimed to assess whether individuals with significant renal impairment assessed by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) form...

BACKGROUND The performance of the Cockcroft-Gault (CG) equation, the Modification of Diet in Renal Disease (MDRD) formula, and the Chronic Kidney Disease Epidemiology Collaboration equation (CKD-EPI) was evaluated in body mass index (BMI) categories. MATERIAL AND METHODS In this retrospective cohort study in diabetic patients, creatinine clearance was measured by collecting 24-hour urines. Re...

Background. The limitations of the laboratory evaluations of kidney function (KF) are well recognized. Therefore, in clinical practice, various mathematical formulas are applied for the bedside estimation of KF. Aim. The aim of this study was to compare the calculated KF function derived from two different formulas i.e. the Cockcroft-Gault (CG) formula and the shorten version of Modification of...