نتایج جستجو برای: cognitive impairment cranial irradiation
تعداد نتایج: 438126 فیلتر نتایج به سال:
INTRODUCTION Small cell carcinoma constitutes the most aggressive type of lung cancer, with the greatest propensity for early disseminated disease. Although commonly neglected due to its rarity and the presence of other comorbidities, cases of iris metastasis from small cell lung cancer have been reported in the literature. CASE PRESENTATION We present the case of a 76-year-old female. Once d...
Survivors of childhood cancer frequently experience cancer-related cognitive dysfunction, commonly months to years after treatment for pediatric brain tumors, acute lymphoblastic leukemia (ALL), or tumors involving the head and neck. Risk factors for cancer-related cognitive dysfunction include young age at diagnosis, treatment with cranial irradiation, use of parenteral or intrathecal methotre...
Cranial irradiation is widely used in cancer therapy, but it often causes cognitive defects in cancer survivors. Oxidative stress is considered a major cause of tissue injury from irradiation. However, in an earlier study mice deficient in the antioxidant enzyme extracellular superoxide dismutase (EC-SOD KO) showed reduced sensitivity to radiation-induced defects in hippocampal functions. To fu...
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Cranial irradiation for the treatment of brain cancer elicits progressive and severe cognitive dysfunction that is associated with significant neuropathology. Radiation injury in the CNS has been linked to persistent microglial activation, and we find upregulation of pro-inflammatory genes even 6 weeks after irradiation. We hypothesize that depletion of microglia in the irradiated brain would h...
Pediatric posterior fossa tumor (PFT) survivors who have been treated with cranial radiation therapy often suffer from cognitive impairments that might relate to IQ decline. Radiotherapy (RT) distinctly affects brain regions involved in different cognitive functions. However, the relative contribution of regional irradiation to the different cognitive impairments still remains unclear. We inves...
objectives: the current study was performed to investigate the relationship between mental impairment and each component of activity of daily living (adl) in elderly residents of the kahrizak charity foundation. methods & materials: standardized iranian mini mental examination and barthel index were used to assest cognitive status and adl in 184 elderly residents of kahrizak, respectively. resu...
conclusions our findings show that premedication with passiflora incarnata reduces anxiety as well as melatonin. however, melatonin causes less cognitive impairment compared to passiflora incarnata. results there were no statistically differences between groups in vas (p > 0.05). however, the mean score of pain was higher in the melatonin group compared to the pssiflora incarnata group when dis...
background and purpose: delirium is a clinical syndrome with cognitive disorder, which occurs within a short time in the admitted patients, specially the elderly. regarding the fact that one third of the delirium incidences is preventable, applying nursing preventive measures is an issue of fundamental importance. the present study aimed to perform a systematic review over the nursing preventiv...
Therapeutic irradiation is commonly used to treat primary or metastatic central nervous system tumors. It is believed that activation of neuroinflammatory signaling pathways contributes to the development of common adverse effects, which may ultimately contribute to cognitive dysfunction. Recent studies identified the chemokine (C-C motif) receptor (CCR2), constitutively expressed by cells of t...
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