abstract colchicum kotschyi boiss (colchicaceae) is one of the sixteen iranian native colchicum species, containing considerable amount of colchicine. to study the effect of different nutrient levels on corm yield and colchicine content of colchicum kotschyi boiss under open field soilless culture, an experiment was performed in a randomized complete design at the horticultural research station...

This brief history of the use of extracts of Colchicum autumnale in the treatment of gout had its origin in some research relative to the metabolism and mode of action of colchicine. It was interesting to review this history in order to develop a background, and thus to learn what ancient authorities and later observers knew about this drug. We shall review the evidence for the identity of cert...

Ailevi Akdeniz Ateşi; otozomal resesif genin kalıtımıyla, doğuştan gelen ve immün sistemi etkileyen bir antiinflamatuvar hastalıktır. Hastalık, 16. kromozomdaki MEFV geninde oluşan mutasyon sonucu gözlenir. Tekrarlayan ateş serözit ataklarla seyreden Colchicum autumnale L. isimli tıbbi bitkinin tohumlarından elde edilen kolşisin alkaloid günümüzde AAA tedavisinde yaygın olarak kullanılmakta etk...

A heifer developed severe signs of acute gastrointestinal irritation 48 hr after ingesting fresh leaves of Colchicum autumnale growing on a damp meadow. Confirmation of the suspected toxicosis was obtained by detecting colchicine in serum and urine using liquid chromatography coupled with tandem mass spectrometry using atmospheric pressure chemical ionization. Although the serum colchicine conc...

Autumn crocus poisoning of cattle is characterized by severe diarrhea caused by alkaloid colchicine. Previously, we examined pathologically this poisoning in cattle and reported that enterotoxic lesions were closely associated with apoptosis. To examine enterotoxicity of autumn crocus more precisely, a reproductive study was performed using guinea pigs and mice, and pathological findings associ...