BACKGROUND Family history is important for identifying candidates for high risk cancer screening and referral for genetic counseling. We sought to determine the percentage of individuals who would be eligible for high risk cancer screening or genetic referral and testing if family history includes an extended (vs limited) family history. METHODS Family histories were obtained from 626 women a...

background: during the past few years, hesa-a, a herbal-marine mixture, has been used to treat cancer as an alternative medicine in iran. however, weight of the evidence is not sufficient to accept or refuse the use of this compound as a cytotoxic drug. we investigated the selective anticancer effects of hesa-a on breast, prostate, colon, and glioblastoma multiforme (gbm) neoplastic cell lines....

Background: RNA 5-methylcytosine (m5C) methyltransferases NSUN1 is a member of the NOP2/SUN (NSUN) methyltransferase family. Studies have found that expression elevated in breast and colon cancer can predict poor prognosis. However, gene has only been studied few tumors.

In a systematic effort to identify a potent antiproliferative agent, four complexes of vanadium containing maltol and deferiprone ligands were synthesized and evaluated for their cytotoxic activity against five human and animal cancer cell lines, including human breast cancer cells (MCF-7), human cervix epithelial carcinoma (HeLa), human colon cancer cell line (HT-29), human leukemia cell line ...

aretaeus of cappadokia, lived in an era when cancer was already a disease, well known for its deadly outcome. inside his momentous treatise, composed of 8 books, he had outlined various types of cancer. he had understood cancer’s fatality and proposed some curative treatments. our manuscript composes the fragments related to cancer, in an effort to present aretaeus’ views on the matter.  he had...

BACKGROUND Glycosylation of the tumour cell surface is of importance in metastasis formation as indicated by lectin-binding studies. In particular, binding of the lectin HPA is associated with metastasis formation, both in clinical studies and in xenograft models of breast and colon cancer. Here we examined if there is an association between the HPA-positive glycotopes of metastasizing cancer c...

Cancer is one of the most fatal diseases in human beings which annually leads to death of 30000 individuals in Iran. Prevention, diagnosis and treatment of cancer is one of the major scientific challenges all around the world. It seems that increased incidence of several cancers such as colon and prostate and their mortality are connected with obesity. It is suggested that obesity and metabolic...

there is a good literature confirming the effects of social capital on different health domains. the increase in different types of cancer has caused scientists to encounter a number of issues regarding the reasons of affliction by this disease. the aim of this empirical research was to study the causal aspects of social capital of iranian patients with cancer.the study was a causal-comparative...

INTRODUCTION The aim of this study was to investigate the utilization of breast, colon and prostate cancer screening in the adult Croatian population in a period without national cancer screening programs, with a special interest in respondents' rural versus urban origin. METHODS Self-reported screening utilization was investigated in the Croatian Adult Health Survey, which collected health-r...