BACKGROUND Malaria is a serious public health problem in sub-Saharan Africa and is a leading cause of morbidity and mortality. AIM To estimate the economic burden of malaria in rural households. SETTING The study was conducted in Gwanda district of Matabeleland South in Zimbabwe. A total of five malarious wards and all their households were selected for the study frame, out of which 80 hous...

Malaria is endemic in 91 countries. Maximum mortality is associated with Plasmodium falciparum malaria and more than 8,00,000 deaths occur in children less than five years of age1. P. falciparum usually presents with severe or complicated malaria, which presents as fever, chills, shock, hepatic failure, renal failure, cerebral malaria and malarial sepsis. It leads to 100% mortality if left untr...

CD163 is an acute-phase-regulated monocyte/macrophage membrane receptor expressed late in inflammation. It is involved in the haptoglobin-mediated removal of free hemoglobin from plasma, has been identified as a naturally soluble plasma glycoprotein with potential anti-inflammatory properties, and is possibly linked to an individual's haptoglobin phenotype. High levels of soluble CD163 (sCD163)...

Angioimmunoblastic T-cell lymphoma (AITL) is a rare and aggressive form of peripheral (PTCL). It can present with signs symptoms that have broad differentials, including fevers, night sweats, skin rashes. In this case report, we an interesting young male Nigerian descent recently treated malaria who presented such picture was complicated, due to inconclusive excisional biopsy for lymphoma. He l...

OBJECTIVE Despite a substantial disease burden, little is known about the natural history of complicated falciparum malaria. Therefore, the present prospective study was undertaken to assess the clinical course, outcome, and resolution time of various complications of falciparum malaria. METHODS This prospective study has been conducted in a tertiary health care institution with high prevalen...

Introduction Malaria in very young children is a major therapeutic challenge in highly endemic areas where initial infection can occur in the first few months of life. Because active immunity has not begun to be established, infants are most at risk from falciparum malaria, and it has been estimated by the World Health Organisation that up to 1096 of all infant mortality in Africa is directly o...

An estimated 300 million cases of malaria occur each year, annually accounting for 1.5 to 2.7 million deaths (1). Most of these deaths are due to infection with Plasmodium falciparum and occur among children and pregnant women in the developing world, especially sub-Saharan Africa. Unfortunately, mortality during severe or complicated malaria still exceeds 10% to 30% (2). Due to increasing resi...

BACKGROUND We evaluated albumin cobalt binding (ACB) assay also known as Ischaemia Modified Albumin (IMA) assay as a prognostic marker for severe malaria in a medical college setting. METHODS Consecutive adult patients admitted with both vivax and falciparum malaria were evaluated with ACB assay at the time of admission. Detailed work up and individual patient directed management were institu...

Background: The spectrum of clinical picture of malaria ranges from the most benign febrile illness, which is completely curable with a simple course of chloroquine tablets to the most serious and life-threatening illness, even with very drastic therapeutic measures. That is the reason that has led to the studies from different parts the world to find out the clinical and laboratory parameters ...

A 19-year-old male presented with fever, oliguria and purpuric lesions involving both hands. The patient was diagnosed as a case of purpura fulminans with disseminated intravascular coagulation due to complicated Falciparum malaria. The case is presented to sensitize the physicians to keep malaria as a differential in cases of fever with purpura fulminans.