The reaction of 3-chloropropyl boehmite nanoparticles with caffeine and sulfuric acid afforded BNPs-3-propyl-imidazolopyridinium hydrogen sulfate [BNPs-Caff]HSO4 as a new BNPs-supported ionic liquid (IL) catalyst. [BNPs-Caff]HSO4 proved to be an efficient heterogeneous catalyst for the synthesis of pyrazolopyranopyrimidines via a one-pot four-component reaction of...

a simple and efficient one-pot, three-component strecker reaction of protected amino acids, aromatic aldehydes, and trimethylsilyl cyanide has been developed for the synthesis of chiral α-amino nitriles. the reaction was carried out in the presence of catalytic amount of phosphotungstic acid (h3[p(w3o10)4]) as an environmentally friendly catalyst.

silica-bonded n-propyltriethylene-tetramine (sbnptt) was found as an efficient solid base for the synthesis of 2-amino-5-oxo-5,6,7,8-tetrahydro-4h-chromenes. chromene derivatives were obtained via the three-component condensation reaction of aromatic aldehydes, malononitrile, and dimedone at 80 oc under solvent-free conditions. the heterogeneous solid base showed much the same efficiency when u...

An aqueous solution of boric acid, as an efficient and green catalytic system, was efficiently utilized four-component cascade reaction of aryl aldehydes, dimedone, β-ketoesters and ammonium acetate to give hexahydroquinolines. By the reaction of boric acid with water, H+ was generated and efficiently catalyzed the reaction under mild and green condition. Also, optimization of the reaction cond...