Background and Aim: Chairside computer-aided design/computer-aided manufacturing (CAD/CAM) systems have become considerably more accurate, reliable, efficient, fast, and prevalent since 1985 when CEREC was introduced. The inceptive restorative material option for chairside CAD/CAM restorations was limited to ceramic blocks. Today, restorative material options have been multiplied and include me...

A Digital Microfluidic Biochip (DMFB) offers a promising platform for medical diagnostics, DNA sequencing, Polymerase Chain Reaction (PCR), and drug discovery and development. Conventional Drug discovery procedures require timely and costly manned experiments with a high degree of human errors with no guarantee of success. On the other hand, DMFB can be a great solution for miniaturization, int...

SPECIALTY GRAND CHALLENGE article Front. Drug Discov., 28 July 2021Sec. In silico Methods and Artificial Intelligence for Discovery Volume 1 - 2021 | https://doi.org/10.3389/fddsv.2021.728551

background: the aim of this study was to determine the microtensile bond strength (μtbs) of ceramic and composite computer aided design‑computer aided manufacturing (cad‑cam) blocks bonded to dentin using different adhesive strategies. materials and methods: in this in vitro study, 30 crowns of sound freshly extracted human molars were sectioned horizontally 3 mm above the cementoenamel junctio...