The value of carbohydrate deficient transferrin (CDT) as the most direct and most accurate indicator of alcohol abuse has been amply demonstrated in the scientific literature. The CDT assay used by GIB Laboratories to assess serum samples for significant levels of alcohol abuse was validated using 184 clinically defined positive and 203 clinically defined negative specimens. Using a defined cut...

1. Describe the principle and procedure. 2. Compare and contrast reagent strip characteristics among manufacturers. 3. Interpret results. 4. Define expected normal values. 5. Suggest causes for abnormal findings. 6. Identify sources of error. 7. Suggest appropriate confirmatory tests. 8. Correlate results of chemical tests with those of physical examination. 9. Predict findings of microscopic e...

CITE enzyme-linked immunosorbent assay (ELISA) was an unacceptable screening test for failure of passive transfer because of poor sensitivity. SNAP ELISA and glutaraldehyde coagulation tests are more appropriate screening tests. Specificity of the SNAP ELISA is better than the glutaraldehyde coagulation test. A second confirmatory test should be considered when using the glutaraldehyde coagulat...

Human immunodeficiency virus (HIV) is a major cause of death globally. It causes acquired immunodeficiency syndrome (AIDS) characterized by relentless destruction of human immune system. HIV is a retrovirus that primarily infects the CD4 presenting cells of human immune system, such as, macrophages and dendritic cells. People die of AIDS because the disease remains undetectable for a long time ...

OBJECTIVE To determine the prevalence of Hepatitis-B, Hepatitis-C and Human Immunodeficiency infections in replacement blood donors. MATERIALS AND METHODS From January 2004 to December 2011, 108,598 apparently healthy donors donated blood at our Blood Bank. Screening was done by Microparticle Enzyme Immuno Assay (MEIA) method on Axsym System (Abbott Diagnostic, USA) and in year 2011 by Chemil...