Objective: to describe the case of a Brazilian Amazon woman presenting macroscopic melanosis coli associated with the chronic use of laxative herbal teas. Case Report: a 48years-old woman was referred for evaluation of a diffuse abdominal pain, intestinal meteorism, gastric plenitude, eructation and chronic constipation. The patient confirmed the use of laxatives and herbal teas as auto-medicat...

Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. It is clinically manifested as a blue-gray discoloration of the skin and mucous membranes in a cephalo caudal progression...

Congenital melanocytic nevi are commonly encountered in clinical practice. Although the development of malignant melanoma arising in small and intermediate congenital melanocytic nevi is rare, there is a significant risk of malignant degeneration associated with large congenital melanocytic nevi, in particular those that arise on the torso in the so-called "bathing trunk" distribution, where th...

Iris melanoma is a primary intraocular tumor with a high potential risc for metastasis, characterized by the presence of a single or a multiple hyperpigmentation focal areas, or diffuse hyperpigmentation of the anterior epithelium of the iris. This hyperpigmentation is due to an abnormal growth and proliferation of melanocytes. However, not any hyperpigmentation should be handled as a melanom, ...

Neurocutaneous melanosis (NM) coexisting with the Dandy-Walker complex (DWC) is a rare condition, with fewer than 15 cases reported in the literature. The authors present a case of an infant with NM and DWC suffering from progressive brainstem compression following ventriculoperitoneal (VP) shunt placement for hydrocephalus. This 1-year-old boy with congenital melanocytic nevi had met normal de...

Oculodermal melanocytosis (ODM) is a congenital melanocytic hyperpigmentation of the face and ocular tissues. The eponym naevus of Ota as described by Otal has been used interchangeably with ODM and ocular melanosis (OM) in many reported cases. The original definition by Ota included patients with and without ocular involvement. For these reasons, we will refer to the term oculodermal melanocyt...

neurocutaneous melanosis (ncm) is a rare, congenital non-hereditary syndrome, characterized by multiple pigmented nevi. we report the radiologic findings of a newborn who had extensive cutaneous melanotic nevus with satellite lesions in the brain. ultrasound showed multiple echogenic foci in the cerebral parenchyma. subsequent mri confirmed these lesions as characteristic deposits of melanin. t...