The term high content screening (HCS) has become synonymous with imaging screen using automated microscopes and automated image analysis. The term was coined a little over 10 years ago, since then the technology evolved considerably and has established itself firmly in the drug discovery and development industry. Both the instruments and the software controlling the instruments and analyzing th...

■ The mobile Internet represents a massive opportunity for mobile operators and content providers. Today there are more than 2 billion mobile subscribers, with 3 billion predicted by the end of 2007. However, despite significant improvements in handsets, infrastructure, content, and charging models, mobile users are still struggling to access and locate relevant content and services. An importa...

Drug discovery in its early history used to be conducted mainly in a target-agnostic fashion, focusing on qualitative readouts from a living system -cells, tissue, or organisms -and asking the question, ‘Did this entity affect the phenotype?’. With the rise of molecular biology in the early 1980s and an ever more powerful genomics toolkit from the 1990s, there was a marked shift away from pheno...

Current technology development in mobile computing and upcoming application stores enable an easy development and distribution of mobile applications. This leads to an increasing number of available applications and to the user’s problem of content discovery. Recommender systems aim at guiding users to relevant items. Currently, recommender systems that suggest mobile applications neglect that ...