Manufacturing companies are facing a broad variety of challenges caused by a dynamic production environment. To succeed in such an environment, it is crucial to minimize the loss of time required to trigger the adaptation process of a company’s production structures. This paper presents an approach for the continuous monitoring of production structures by neurologic principles. It enhances clas...

This study is pertaining to the production of penicillin G acylase (PGA) by Bacillus subtilis 8105MU331 in which PGA gene, under the control of thermal-induced promoter, was integrated. The key process parameters including induced-temperature, induced-time, and culture temperature were optimized in flask culture. A three-stage cultivation process was developed for PGA production with the expres...

Integration of the management of production systems has been considered one of the most relevant aspects in the automation process. In this work, authors propose to use abstraction mechanisms of the dynamics of continuous systems, to represent the behavior of processes (hybrid systems), and in this way, to supervise whole process. This work describes the implementation of mechanisms to supervis...

The optimum use of the upstream resources, production corresponding to the market demands, and structural constraints for the optimum production with the less wastes during the most rapid time required by the market which finally result in the more profit for the shareholders are considered as the major objectives of this research. In this research, for the purpose of increasing the efficiency ...

İşletmelerin küresel ekonomik rekabet ortamında faaliyetlerini gerçekleştirmesi, işletmelerin bilgi teknolojilerine dayalı mal ve hizmet üretim süreçleri oluşturmalarını zorunlu hale getirmektedir. Artan teknoloji kullanımı karşısında gerçekleştirilen faaliyetlere ait alt işlem süreçlerinin kontrol altına alınması yönetilmesi iç sistemlerine kritik bir rol yüklemektedir. Daha fazla sürecin veri...