A copper-catalyzed asymmetric propargylic amination with a chiral ketimine P,N,N-ligand that proceeds via decarboxylation of propargyl carbamates has been developed. The reaction can be performed under the mild condition for a broad range of substrates, providing the corresponding propargylic amines in high yields and with up to 97% ee. This reaction represents a new and facile access to optica...

Although copper has been the subject of numerous researches which have demonstrated that it is essential for normal hemoglobin formation, there have been very few attempts to discover the type of compound in which the element occurs in the case of red blooded animals. Warburg and Krebs (1) approached the problem in experiments on what was referred to as loosely bound copper in blood serum. Usin...

Although copper has been the subject of numerous researches which have demonstrated that it is essential for normal hemoglobin formation, there have been very few attempts to discover the type of compound in which the element occurs in the case of red blooded animals. Warburg and Krebs (1) approached the problem in experiments on what was referred to as loosely bound copper in blood serum. Usin...

OBJECTIVE To estimate the prevalence of beryllium sensitization among former and current Department of Defense workers from a conventional munitions facility. METHODS Participants were screened by using Beryllium Lymphocyte Proliferation Test. Those sensitized were offered clinical evaluation for chronic beryllium disease. RESULTS Eight (1.5%) of 524 screened workers were found sensitized t...

Costs for workers’ compensation benefits in California have increased sharply in recent years, following periods of decline and stability. California was already one of the most expensive states for total costs per injured worker and for a number of types of testing and treatment in the midto late 1990s. For example, a series of multi-state studies revealed that California has the second highes...

The Front Cover shows an “O2 grasshopper” captured by two “Copper scorpions” using their strong claws and tails (outer-sphere hydrogen bonds). As the key intermediate in biological oxygenation, trans-1,2-peroxodicopper adduct was mimicked a variety of molecular copper complexes. structure-activity models hydrogen-bond-assisted tetradentate copper(I) chloride complexes were established, fundamen...

Oxygen Evolution Catalysts Copper complexes, as a kind of molecular catalysts bio-inspired from the copper O2-activating enzymes, are attractive targets for water oxidation, which could undergo facile and reversible O-O bond formation cleavage under mild conditions. In article number 2201018, Jing-Xin Jian, Qing-Xiao Tong, co-workers investigate three copper(II) complexes oxygen evolution in ph...

Background: The workers of mines, during a working day, are exposed to stress and psychological pressure that certainly affect the efficiency of their work. This study aimed to determine the level of stress, anxiety, and depression in workers of one copper mine in Kerman Province, Iran. Materials and Methods: In this cross-sectional study, 250 workers of the operation unit of one copper mine...

Tribochemical reactions frequently are decisive for friction and wear. In article number 2001673 by Christian Greiner co-workers, such investigated between copper its oxides in contact with sapphire. The authors find that freshly formed beneficial reducing friction, especially as sliding progresses. Sliding even provides enough energy a reduction of oxide to metallic copper.