AIMS To evaluate the age-related variations of ocular parameters in Korean subjects. METHODS We recruited 314 normal subjects who visited the department of Ophthalmology between January 2007 and October 2007. Refraction, axial length, corneal curvature, white-to-white distance, anterior chamber depth, corneal endothelial cell density, and retinal nerve fiber layer (RNFL) thickness were measur...

PURPOSE The aim of this study was to quantify epithelial, stromal, and endothelial cell density, and subbasal nerve morphology in young patients with type 1 diabetes mellitus with and without diabetic retinopathy. METHODS A total of 28 young patients (mean age, 22.86 ± 9.05 years) with type 1 diabetes, with (n = 18) and without (n = 10) retinopathy, and 17 age-matched healthy control subjects...

PURPOSE To determine how stimuli that increase corneal endothelial cell proliferation of human corneas in culture relate to changes in endothelial cell density in the central and peripheral cornea. METHODS Human donor cadaver corneas not suitable for transplantation were divided into four pie-shaped wedges and incubated at 37 degrees C in medium supplemented with fetal bovine serum, epidermal...

Maintenance of corneal transparency is crucial for vision and depends mainly on the endothelium, a non-proliferative monolayer of cells covering the inner part of the cornea. When endothelial cell density falls below a critical threshold, the barrier and "pump" functions of the endothelium are compromised which results in corneal oedema and loss of visual acuity. The conventional treatment for ...

Objectives: To compare corneal endothelial cell changes namely, endothelial cell density (ECD), percentage polymegathism (CV) and pleomorphism (6A) along with central corneal thickness (CCT) in patients of type 2 diabetes mellitus with normal age and sexmatched subjects. To correlate corneal endothelial changes with diabetic retinopathy status, total duration of disease and glycemic control (Hb...

background: new blood vessels formation is a critical step in tumor progression. vascular density affects the clinical outcome and prognosis of malignant tumors. the aim of this study was to investigate the relation between the vascular endothelial growth factor (vegf) expression and vascular density with the clinical and histopathologic features in oral squamous cell carcinoma (oscc).   method...

BACKGROUND The corneal endothelial structure may be changed in diabetic patients, but the results were variable. OBJECTIVE To compare the corneal endothelial structure including endothelial cell density, polymorphism, andpleomorphism, in diabetic and non-diabetic subjects. MATERIAL AND METHOD The corneal endothelial structure of diabetic and non-diabetic subjects were measured by specular m...

PURPOSE To evaluate retrospectively the corneal endothelium in 15 eyes which showed clear cornea for 20 years or longer after penetrating keratoplasty. METHODS The corneal endothelium was investigated in 15 eyes. The causative lesion had been keratoconus in 10 eyes and herpetic keratitis in 5 eyes. At the time of surgery, the patients were aged from 6 to 45 years, average 25.3 +/- 10.4 years....