Corneal ulcers are a major cause of blindness worldwide. A recent eye health care concern is the increasing incidence of contact lens induced corneal ulcers. Delay in the diagnosis and management of corneal ulcers can cause severe visual loss, therefore an early ophthalmologist visit and timely administration of antimicrobial agents can prevent visual loss. Factors associated with increased ris...

Introduction: To effectively prevent blindness in patients with corneal ulcer, a proper understanding of risk factors predisposing to ulceration, and clinical and microbial characteristics of the disease is essential. Aim is to know the age and sex distribution of corneal ulcer. To identify the predisposing factors, etiological factors contributing to corneal ulcer. To study the clinical featur...

OBJECTIVE To describe the use of a porcine urinary bladder acellular matrix for surgical reconstruction of the cornea in cases of canine and feline deep corneal ulcers, and feline corneal sequestra. MATERIALS AND METHODS Twenty-seven dogs and three cats with deep corneal ulcers and seven cats with corneal sequestra were included in the study with overall 38 eyes. For each patient, the necroti...

INTRODUCTION The aim of this case series is to describe the clinical course of 2 patients with Neisseria meningitidis corneal ulcers. CLINICAL PICTURE A 49-year-old man (Patient 1) and a 22- year-old man (Patient 2) both experienced eye pain and were found to have corneal ulcers with surrounding infiltrate and ground-glass appearance. Gram-negative diplococci were seen in the first case. N. m...

Canine amniotic membrane (AM) transplantation in conjunction with a third eyelid flap was used to promote healing of created deep corneal ulcers in 6 normal mongrel dogs. The healing was compared with the healing of created ulcers in the other eye of the same dog that were treated only with the third eyelid flap. A minimum of 60 days interval was allowed between the two treatment procedures in ...

AIM To observe the therapeutic effect of corneal collagen cross-linking (CXL) in combination with liposomal amphotericin B in fungal corneal ulcers. METHODS New Zealand rabbits were induced fungal corneal ulcers by scratching and randomly divided into 3 groups, i.e. control, treated with CXL, and combined therapy of CXL with 0.25% liposomal amphotericin B (n=5 each). The corneal lesions were ...

OBJECTIVE Corneal ulcers are commonly encountered in pinnipeds. Prolonged oral antibiotics and topical ophthalmic solutions may not be practical to administer, and novel treatment techniques are desired. Thermodynamic gels are a potential solution because they hold antimicrobials at the site of injection, slowly releasing drug. This study investigated the clinical efficacy of antibiotic-impregn...