The skin is an indispensable barrier which protects the body from the uncontrolled loss of water and solutes as well as from chemical and physical assaults and the invasion of pathogens. In recent years several studies have suggested an important role of intercellular junctions for the barrier function of the epidermis. In this review we summarize our knowledge of the impact of adherens junctio...

Phenothiazines have been associated with various ocular adverse effects, in particular cataract and corneal deposits. Several effects are vision threatening. Awareness of these effects, in particular by Psychiatrists and Ophthalmologist, is essential for prompt diagnosis and appropriate treatment. We report two patients presented to us with corneal deposits and lenticular opacities following lo...

OCULAR complications occur in 10 to 20 per cent. of patients with periarteritis nodosa (Gaynon and Asbury, 1943; Wise, 1952), but so far very few cases of either corneal ulceration, corneo-scleritis, or scleritis have been documented, which have been associated with either periarteritis nodosa or the Wegener variety of non-healing granuloma of the nose (Harbert and McPherson, 1947; Ingalls, 195...

To the Editors of THE BRITISH JOURNAL OF OPHTHALMOLOGY. SIRs,-I have read with interest Mr. Affieck Greeves' letter in the correspondence section of the July number criticising the corneoscleral suture in cataract extraction. (See Brit. Ji. of Ophthal., May, 1938.) I agree with his preference for a conjunctival stitch on the grounds that a more liberal conjunctival flap is obtainable by this me...

ELECTRO-OCULOGRAPHY has been established as a valuable clinical procedure for measuring indirectly the standing corneo-fundal potential, of importance in the investigation of retinal and choroidal function. Although the technique of clinical recording is not very complicated, the load of a great many records is a burden for the technical staff of an electro-diagnostic clinic. Semiautomatic reco...

PURPOSE To describe a surgery technique for removing donor sclera tissue after corneo-scleral button excision. RESULTS The extrusion technique is easy to perform. It allows the complete scleral extraction its total clean up to be performed, as well as making easier to isolate the retina and uveal tissue. This technique could have an important role in the anatomical and morphological study of ...

We demonstrate an application of high-speed swept source optical coherence tomography for vessel visualization in the anterior segment of the human eye. The human corneo-scleral junction and sclera was imaged in vivo. Imaging was performed using a swept source OCT system operating at the 1050nm wavelength range and 100kHz A-scan rate. High imaging speed enables the generation of 3D depth-resolv...

AIMS To assess ocular surface changes in patients with chronic renal failure (CRF), to compare the results with the degree of corneo-conjunctival calcium deposits, and to determine whether precipitation of calcium salts predisposes ocular surface modifications. METHODS Impression cytology from 50 CRF patients on regular haemodialysis and 22 age and sex matched control subjects were studied. S...