A61-year-old man with a history of coronary artery aneurysms was referred to our institution for evaluation of dyspnea on exertion. Coronary artery bypass of the aneurysms had been performed 2 years earlier. Although it was reported that the aneurysms had been ligated, coronary angiography revealed large residual aneurysms of the right and left circumflex arteries (top left, Figures 1 and 2), w...

A 78-year-old man with end-stage kidney disease secondary to autosomal dominant polycystic disease (ADPKD) on haemodialysis, presented to our institution following a myocardial infarction. He was known to have cystic involvement of his liver and spleen, significant mitral regurgitation secondary to mitral valve prolapse, and a distant history of abdominal aortic aneurysm repair. There was no fa...

Coronary artery aneurysm is defined as any coronary artery dilation exceeding the diameter of normal adjacent segments or the diameter of the largest coronary artery by 1.5 times. Giant coronary aneurysm refers to an aneurysm with a diameter larger than 20 mm. Giant coronary artery aneurysms have an incidence of 0.02%-2%. Here we describe a patient who had giant coronary aneurysms involving all...

Real-time cross-sectional echocardiographic studies revealed the presence of coronary artery aneurysms in five patients with mucocutaneous lymph node syndrome. These lesions appeared as circular echo-free spaces with clearly-defined borders in sites corresponding to angiographically proven aneurysms. In 15 normal subjects who were studied only by noninvasive methods, and in 17 who had normal co...

BACKGROUND Kawasaki disease (KD) is an acute systemic vasculitis that occurs in children and may lead to cardiovascular morbidity and mortality. Progressive coronary dilatation for at least 2 months is associated with worse late coronary outcomes in patients with KD having medium or giant aneurysms. However, the risk factors and occurrence of progressive coronary dilatation in patients with KD ...

Coronary artery aneurysms or ectasias are dilatations of arterial segments, which are typically incidentally identified at angiography. Several large clinical series have described the epidemiology and natural history of these malformations. The most common etiologic factor for coronary aneurysms is atherosclerotic coronary artery disease, but they can also be congenital or secondary to inflamm...

conclusions coronary artery aneurysm should be a differential diagnosis in cases of mediastinal cyst and mass lesion. case presentation a 32-year-old woman presented with edema of the upper and lower limbs, palpitation, and chest pain, and was diagnosed with a giant right coronary artery aneurysm that had initially mimicked a mediastinal cyst. although computed tomography (ct) suggested a media...

Drug-eluting stents (DES), which locally elute antiproliferative drugs, can dramatically inhibit neointimal growth. However, several pathological studies have indicated that DES may delay healing after vascular injury, and DES implantation may be theoretically associated with a risk of coronary artery aneurysm formation. Coronary aneurysms have been reported from 3 days to up to 4 years after D...

OBJECTIVE Coronary artery aneurysms are the major complication of Kawasaki disease (KD). Matrix metalloproteinases (MMPs) regulate remodeling and degradation of the extracellular matrix. We hypothesized that MMP-9 expression is increased in acute KD aneurysms when compared with KD nonaneurysmal arteries and arteries from control children. METHODS AND RESULTS MMP-2, MMP-9, tissue inhibitor of ...