Objective: The objective of the present study was to evaluate the possible analgesic and anti-inflammatory activity of the root of Cucumis callosus (Rottl.) Cogn. (Cucurbitaceae) using different animal models. Materials and Methods: The methanol extract of the identified root part of plant Cucumis callosus was used for the evaluation of antinociceptve effect using three animal models namely; ac...

Calcium hydroxide is advocated as an intracanal medication for various purposes, including prevention of posttreatment symptoms. This study assessed whether calcium hydroxide had a pain-controlling effect at different times when compared with no intracanal medication. One hundred forty patients participated. Conditions diagnosed were pulp/periapical pathosis with or without symptoms. At least p...

Shorea robusta Gaertn. f. (Sal) is one of the most important traditional Indian medicinal plants. The resin of the plant has been used in the treatment of inflammation in folklore medicine. In the present study, ethanolic extract (70%) of S. robusta resin (SRE) was investigated for its anti-inflammatory and antipyretic activities. Acute inflammation was produced by carrageenan-induced hind paw ...

Aim: To investigate the analgesic and anti-inflammatory properties of seed extracts of Diplocyclos palmatus (L) C. Jeffrey. Methods: Three extracts of different polarity of Diplocyclos palmatus (L) C. Jeffrey seeds were tested for their analgesic and anti-inflammatory activities. Analgesic activity was evaluated using the hot plate and acetic acid-induced writhing in mice. Antiinflammatory acti...

BACKGROUND Traditional Chinese medicine Taraxacum officinale has been widely used to treat various inflammatory diseases. Taraxasterol is one of the main active components isolated from Taraxacum officinale. Recently, we have demonstrated that taraxasterol has the in vitro anti-inflammatory effects. This study aims to determine the in vivo anti-inflammatory effects of taraxasterol against anima...

A pattern-recognition technique has been used to determine structure-activity relationships for antiinflammatory steroids. Experimental results using the human vasoconstrictor test of McKenzie and Stoughton and the rat granuloma cotton pellet method of Meier were correlated with the various substructural descriptors. Steroids were classified into two categories according to potency, and a patte...

This study was to evaluate anti-inflammatory and analgesic effects of the aqueous extract of leaves of Chromolaena odorata (Asteraceae) collected in Brazzaville-Congo. Acute inflammation was induced by using the carrageenan and formaldehyde models, and chronic inflammation by the cotton pellet induced granuloma model. Analgesic effect was evaluated by using the acetic acid-induced writhing, the...

The anti-inflammatory effect of the plant of Eclipta alba (Family - Asteraceae) was evaluated using carrageenin, mediators such as histamine and serotonin induced paw oedema, and cotton pellet induced granuloma tests for their effect on acute and chronic phase inflammation models in rats. Maximum inhibition (55.85%) was noted at the dose of 500 mg/kg after 3 hr of drug treatment in carrageenin ...

This study reports the beneficial effect of aqueous extract of dried flower buds of Syzygium aromaticum (clove) in acute and chronic inflammation. Inflammation was induced in rats by injecting carrageenan in hind paw or implanting cotton pellet in the axilla. Administration of the extract (1 g/kg body weight) inhibited the formation of oedema induced by carrageenan and decreased granuloma in co...

Rhizome of Costus speciosus has been traditionally used for treating inflammatory and painful conditions. The objective of the present study was to provide a scientific basis for the traditional use. The ethanolic extract of the rhizome of Costus speciosus possesses anti-inflammatory and antipyretic properties. Antiinflammatory property was studied in carrageenan induced paw edema and cotton pe...