To characterize mitochondrial/apoptotic parameters in chronically human immunodeficiency virus (HIV-1)-infected promonocytic and lymphoid cells which could be further used as therapeutic targets to test pro-mitochondrial or anti-apoptotic strategies as in vitro cell platforms to deal with HIV-infection. Mitochondrial/apoptotic parameters of U1 promonocytic and ACH2 lymphoid cell lines were comp...

Exercise training is a neuroprotective strategy in cerebral ischemic injury, but the underlying mechanisms are not yet clear. In the present study, we investigated the effects of treadmill exercise pretreatment on the expression of mitochondrial dynamic proteins. We examined the expression of OPA1/DLP1/MFF/Mfn1/Mfn2, which regulates mitochondrial fusion and fission, and cytochrome C oxidase sub...

The mitochondrial gene for COXII is typically encoded in the organelle genome, however in some members of two unrelated groups, Apicomplexa and Chlorophyceae, cox2 is split into two genes, and both are encoded in the nucleus. Rare genomic changes (RGCs) have acquired popularity as phylogenetic markers, and accordingly this rearrangement of cox2 has been used to infer a possible source of the ap...

Triticeae are renowned for their complicated taxonomy, but their phylogeny is equally intricate and perplexing, and remains largely unresolved. Based on morphology and nucleotide sequences from two plastid genes (rbcL, rpoA), one mitochondrial gene (coxII), and two single-copy nuclear genes (DMC1, EF-G), the most comprehensive hypothesis (both with respect to taxa and data points) of the phylog...

Toward the identification of promoter structures in dicot plant mitochondria, transcription initiation sites were localized by in vitro capping of mitochondrial RNAs from Oenothera berteriana. By this approach at least 15 initiation sites are detectable in the genome. Primary 5'-transcript termini were determined for coxII, atpA, and an 18 S rRNA precursor. Alignment of the sequences surroundin...

Mitochondria are involved in the development and acquisition of a malignant phenotype hematological cancers. Recently, their role pathogenesis multiple myeloma (MM) has been suggested to be therapeutically explored. MYC is master regulator b-cell malignancies such as myeloma, its activation known deregulate mitochondrial function. We investigated impact activity on distinct entities disease tes...

Background: Varicocele (VCL) exerts its impact via enhancing inflammation and down-regulating testicular endocrine and antioxidant statuses. Celecoxib (CCB) is a non-steroidal anti-inflammatory drug (NSAID), which its effects based on the inhibition of cyclooxygenase (COX) enzymes. On the hand, silymarin (SMN) is known for its remarkable anti-oxidative impact. Therefore, present study was desig...

The monophyly and taxonomic validity of some currently accepted genera gall wasps in the Cynipini (Hymenoptera: Cynipidae) are being challenged by recent systematic studies. Here we used morphological molecular data to re-describe revise limits monotypic genus Kokkocynips Pujade-Villar & Melika, previously recorded only from Mexico. We describe a new species Panama, panamensis Medianero Nie...