BACKGROUND Parents who care for young children with chronic conditions are knowledge users. Their efforts, time, and energy to source, consider and monitor information add to the 'invisible' work of parents in making decisions about care, school transitions, and interventions. Little is known or understood about the work of parents as knowledge users. OBJECTIVE To understand the knowledge use...

Crescentic glomerulonephritis (Crgn) is a complex disorder where macrophage activity and infiltration are significant effector causes. In previous linkage studies using the uniquely susceptible Wistar Kyoto (WKY) rat strain, we have identified multiple crescentic glomerulonephritis QTL (Crgn) and positionally cloned genes underlying Crgn1 and Crgn2, which accounted for 40% of total variance in ...

We calculate the homology H∗(Γg,n;Fp) of the mapping class group Γg,n in the stable range. The calculation is based on Madsen and Weiss’ proof of the “Generalised Mumford Conjecture”: Γg,n has the same homology as a component of the space Ω∞CP∞ −1 in the stable range.

Mapping mean and variance of runoff in a river basin L. Gottschalk, I. Krasovskaia, E. Leblois, and E. Sauquet Department of Geosciences, University of Oslo, P.O. Box 1022 Blindern, 0315 Oslo, Norway Cemagref, 3 bis quai Chauveau, CP 220, 69336 Lyon Cedex 09, France Received: 8 December 2005 – Accepted: 19 January 2006 – Published: 9 March 2006 Correspondence to: L. Gottschalk (lars.gottschalk@...

anterior commissure, cc = corpus callosum, cp = caudate putamen, cpd = cerebral peduncle, em = external medullary lamina of thalamus, int = internal capsule, ml = medial lemniscus; fi = fimbria, fr = fasciculus retroflexus, fx = fornix, hf = hippocample fissure; mtt = mammilothalmic tract; sm = stria medularis, vhc = ventral hippocampal commissure. Magnetization Transfer Mapping of Myelinated F...

BACKGROUND N-terminal fragments of mutant huntingtin (htt) that terminate between residues 90-115, termed cleavage product A or 1 (cp-A/1), form intracellular and intranuclear inclusion bodies in the brains of patients with Huntington's disease (HD). These fragments appear to be proteolytic products of the full-length protein. Here, we use an HEK293 cell culture model to investigate huntingtin ...

BACKGROUND AND OBJECTIVES In acute leukemias, chromosomal translocations involving the 11q23 band are frequently, but not invariably, associated with MLL gene rearrangement and their finding is associated with a poor prognosis. We observed two new translocations with a breakpoint in the 11q23 region at standard cytogenetic analysis: a previously undescribed t(3;11)(q21;q23) in a 70-year old wom...

Statistical process control is an excellent quality assurance tool to improve the quality of manufacture and ultimately scores on end-customer satisfaction. SPC uses process monitoring charts to record the key quality characteristics (KQCs) of the component in manufacture. This paper elaborates on one such KQC of the manufacturing of a connecting rod of an internal combustion engine. Here th...

PURPOSE Neuromelanin is a dark pigment granule present within certain catecholamine neurons of the human brain. Here, we aimed to clarify the relationship between contrast of neuromelanin-sensitive magnetic resonance imaging (MRI) and MR relaxation times using T1, T2, and T2* mapping of the lower midbrain. METHODS The subjects were 14 healthy volunteers (11 men and 3 women, mean age 29.9 ± 6....