Trigger factor (TF) is the first chaperone encountered by nascent chains in bacteria, which consists of two modules: peptidyl-prolyl-cis/trans-isomerase (PPIase) domain and a crevice built by both N- and C-terminal domains. While the crevice is suggested to provide a protective space over the peptide exit site of ribosome for nascent polypeptides to fold, it remains unclear whether PPIase domai...

A model is developed to predict the chemistry, corrosion potential and rate of pipeline steels in a crevice formed when a coating disbonds from a pipe surface. The gap of the coating disbonded region is assumed to vary with distance from the mouth. The effect of this gap variation on the chemistry and corrosion rate in the coating disbonded region is investigated in this study through modeling....

RNA protection experiments and the crystal structure of a complex of the large ribosomal subunit from the eubacterium Deinococcus radiodurans with rapamycin, a polyketide compound resembling macrolides and ketolides, showed that rapamycin binds to a crevice located at the boundaries of the nascent protein exit tunnel, near its entrance. At this location rapamycin cannot occlude the ribosome exi...

The corrosion resistance of Cr-containing alloy parts made by additive manufacturing can be significantly improved a post-treatment gas-phase-based infusion concentrated interstitial solute (carbon and nitrogen). We demonstrate this universal approach for the example low-temperature nitrocarburization solid-reagent pyrolysis applied to Alloy 22 (UNS N06022) laser powderbed fusion. show that imp...

J Dent Health Oral Disord Ther 2016, 4(5): 00127 present in the diseased periodontal sulcus: Porphyromonas gingivalis, Fusobacterium nucleatum, Tannerella forsythia, Treponema denticola and various species of prevotellaceae [313]. In addition to these findings, many studies analyzing the microflora of peri-implant crevice in fully edentulous subjects noted the almost total, or total, absence of...