Cofilin and its closely related protein, actin-depolymerizing factor (ADF), are key regulators of actin cytoskeleton dynamics that have been implicated in growth cone motility and neurite extension. Cofilin/ADF are inactivated by LIM kinase (LIMK)-catalyzed phosphorylation and reactivated by Slingshot (SSH)-catalyzed dephosphorylation. Here we examined the roles of cofilin/ADF, LIMKs (LIMK1 and...

The computational approach to the Hirshfeld [Theor. Chim. Acta 44, 129 (1977)] atom in a molecule is critically investigated, and several difficulties are highlighted. It is shown that these difficulties are mitigated by an alternative, iterative version, of the Hirshfeld partitioning procedure. The iterative scheme ensures that the Hirshfeld definition represents a mathematically proper inform...

This paper presents two efficient implementations of fast and pipelined bit-parallel polynomial basis multipliers over GF (2m) by irreducible pentanomials and trinomials. The architecture of the first multiplier is based on a parallel and independent computation of powers of the polynomial variable. In the second structure only even powers of the polynomial variable are used. The par...

Purpose This study aims to extend understanding of business-to-business relationship dynamics by introducing and discussing the phenomenon of a 'negative critical wave' (NCW), defined as a disturbance in a relationship that emerges and develops within or beyond individual working relationships. Design/methodology/approach The dynamics of working relationships in two manufacturing firms in Finla...

organizational culture, as an appropriate context for one's motivation along with a deployment of his talents and abilities can play critical role in increasing an employee's job performance. the main purpose followed in this survey study was to investigate the relationship between agricultural extension experts’ job performance and organizational culture in kerman province, iran. sta...

the purpose of this study was to assess the process of extension program development in iranian agricultural extension system (iaes). the research instrument was a structural questionnaire with close-ended questions which its validity and reliability was confirmed by using expert panel and cranach’s alpha test, respectively. the target population of this research included all extension managers...

in this study, farm level technical efficiency (te) and its determinants were investigated. a stochastic cobb-douglas (cd) production frontier was used to provide estimates of input-oriented te for a sample of 100 rain fed farms in two palestinian governorates. empirical findings showed that the estimated te of the farms in the pooled sample ranged from 35.7 to 95.6%, with a mean value of 72.2%...

The present work is the successful extension of an improved equation of state (EOS) to refrigerant fluids. The objective is the prediction of isothermal and saturated liquid densities of refrigerants. Two temperature-independent parameters appearing in the modified EOS are closely related to critical point properties of refrigerant fluids. Our results showed that, the proposed EOS can predict w...