The aim and objective of orally disintegrating tablets by direct compression method was emerged from desired to provide patient with a conventional mean of taking their medication. Difficulty in swallowing (Dysphagia) is a common problem of all age groups, especially elderly and pediatrics, because of physiological changes associated with these groups of patients. In the present work Ondansetro...

Rivaroxaban (RN) is a recently developed potent oral anticoagulant. The aim of the present study envisages compatibility studies rivaroxaban with crospovidone, sodium startch glycolate, magnesium stearate, talc, microcrystalline cellulose, aerosil, HPMC K100 M, croscarmellose using Differential scanning calorimeter and FTIR spectrophotometer. DSC thermograms, physical mixture individual pharmac...

Surface solid dispersions using water-insoluble carriers like crospovidone, croscarmellose sodium, sodium starch glycolate, pre-gelatinized starch, potato starch and Avicel PH 101 were investigated to enhance the dissolution rate of the glimepiride, a poorly water insoluble drug. The effect of various carriers on dissolution profile was studied using presence absence model. The surface solid di...

In the present work, orodispersible tablets of pheniramine maleate were designed with a view to enhance patient compliance by effervescent method. In the effervescent method, mixture of sodium bicarbonate and tartaric acid (each of 12% w/w concentration) were used along with super disintegrants, i.e., pregelatinized starch, sodium starch glycolate, croscarmellose sodium and crospovidone. The pr...

Introduction: Oro-dispersible tablets are rapidly dissolved in saliva without the need for water and beneficial renal impaired, bedridden psychiatric patients. Objective: The study aimed to formulate oro-dispersible of indomethacin with reduced adverse effects, better patient compliance, faster action, convenience Methods: were prepared using three different super disintegrants; crospovidone, c...

Abstract: Introduction: The present study was carried out to formulate and evaluate orodispersible tablets of Apremilast with a purpose providing better patient compliance geriatric, pediatric, impaired, travelling non-cooperative patients suffering from psoriasis. Such are in need fast easy swallowing drug delivery system. Materials Methods: Apremilast-β-cyclodextrin inclusion complex prepared...

Oral administration of dosage form is the most recommended mode administration, because its self-medication, accurate dose drug, and ease administration. However, trouble swallowing in geriatric patients one major negative this route, which can mentally disrupt patients. The goal study was to use direct compression method make orodispersible tablets sulindac utilizing various doses super disint...

The aim of the present work is to formulate a tablet which disintegrate and dissolve rapidly and give its rapid onset of action: analgesic, antipyretic and anti inflammatory action. Diclofenac sodium is among the most extensively used NSAIDs; employed in musculoskeletal complaints, especially arthritis. Conventional diclofinac sodium tablet available in market are not suitable where quick onset...