GFP and the red fluorescent protein, DsRed, have been combined to design a protease assay that allows not only for fluorescence resonance energy transfer (FRET) studies but also for dual-color crosscorrelation analysis, a single-molecule-based method that selectively probes the concomitant movement of two distinct tags. The measurement principle is based on a spectrally resolved detection of si...

Confocal fluorescence correlation spectroscopy as a time-averaging fluctuation analysis combining maximum sensitivity with high statistical confidence has proved to be a very versatile and powerful tool for detection and temporal investigation of biomolecules at ultralow concentrations on surfaces, in solutions, and in living cells. To probe the interaction of different molecular species for a ...

OBJECTIVE Extraoperative cortical localizing stimulation (LS) is a standard clinical tool used to assess brain function before epilepsy surgery. However, LS can produce unwanted afterdischarges (ADs). We previously have shown that brief pulses of electrical stimulation (BPS) can terminate ADs caused by cortical stimulation. Our objective was to assess whether wavelet-crosscorrelation analysis c...

Sequences with low aperiodic autocorrelation and crosscorrelation are used in communications remote sensing. Golay Shapiro independently devised a recursive construction that produces families of complementary pairs binary sequences. In the simplest case, Rudin–Shapiro sequences, general it what we call Golay–Rudin–Shapiro Calculations by Littlewood show sequences have mean square autocorrelati...

Asymptotic spectral distribution (ASD) of the crosscorrelation matrix is investigated for a large-system asynchronous direct sequence-code division multiple access (DS-CDMA) with random spreading sequences. The crosscorrelation matrix is formed by an infinite input symbol length. Two levels of asynchronism are considered. One is symbol-asynchronous but chip-synchronous (called chip-synchronous ...

This paper describes an extended subband-crosscorrelation(SBXCOR) analysis to improve the robustness against noise. The SBXCOR analysis, which has been already proposed, is a binaural speech processing technique using two input signals and extracts the periodicities associated with the inverse of the center frequency(CF) in each subband. In this paper, by taking an exponentially weighted sum of...

This paper presents new expressions for the bias error and variance introduced by multipath onto the time of arrival estimate obtained using a non-coherent early-late gate discriminator. The results include the effect of front-end bandwidth and early-late gate spacing. We also investigate a blind method for cancelling the multipath, in order to improve the time-of-arrival estimate. Our approach...