Cryptococcus neoformans and C. gattii, the predominant etiological agents of cryptococcosis, can cause life-threatening infections of the central nervous system in immunocompromised and immunocompetent individuals. Cryptococcal meningoencephalitis is the most common disseminated fungal infection in AIDS patients, and C. neoformans remains the third most common invasive fungal infection among or...

Central nervous system (CNS) cryptococcosis is an opportunistic fungal infection that typically occurs in patients with reduced immunological function, such as patients with AIDS, patients receiving organ transplants, or patients receiving corticosteroid and immunosuppressive therapy. CNS cryptococcosis rarely occurs in immunocompetent patients. CNS cryptococcosis is characterized by meningitis...

= Abstract = We herein report an elderly patient with cryptococcosis in the nervous system who presented with cerebellar dysfunction and showed cerebellar parenchymal lesion with adjacent focal meningeal enhancement on the brain CT and the serial brain MRIs. The cerebellar lesion suggests cryptococcal inflammatory reaction or a cerebellar infarction from the arteritis of a branch of the left su...

4. Haight D, Lowella E, Greene J, Sandin R, DeGregorio R, Spiers A. Case report: Cutaneous manifestations of Crytococcosis. Am J Med Sci. 1994;308:192-5. 5. Lynn D, Gurevitch A. Cutaneous manifestations of disseminated cryptococcosis. J Am Acad Dermatol. 1995;32:844-50. 6. Sang H, Zhou WQ, Shi QL, Zang XH, Ni RZ. Disseminated cryptococcosis with extensive subcutaneous nodules in a renal transpl...

Cryptococcus gattii and C. neoformans cause pulmonary and systemic cryptococcosis. Recently, C. gattii was recognized as a distinct pathogen of humans and animals. We analyzed information from 400 publications (1948-2008) to examine whether the fungus occurs globally. Known distribution of C. gattii is possibly limited because specialized reagents for differentiation from C. neoformans are not ...

presses sporangiophore growth, and of the morphologic aspects of nuclear RNA. This latter paper, by a group from the University of Chicago, includes unusually clear electron photomicrographic evidence in support of the authors' claims. The structure of plant cilia and their similarity to those of animals (Manton) and a study of nucleo-cytoplasmic interactions and morphogenesis in Stentor (Tarta...

Cryptococcus neoformans is an encapsulated yeast responsible for disseminated meningitis in immunocompromised hosts. Controversies persist on the existence of primary cutaneous cryptococcosis (PCC) versus cutaneous cryptococcosis being only secondary to hematogenous dissemination. Thus, we reviewed cryptococcosis cases associated with skin lesions reported in the French National Registry. Patie...

Cryptococcosis is an invasive fungal infection, which is more common in immunocompromised patients. However, pulmonary cryptococcosis can occur in immunocompetent patients and should be considered on a differential diagnosis for nodular or mass-like lesions in chest radiograph. Recently, we experienced a patient with pulmonary cryptococcosis, successfully treated with oral fluconazole therapy. ...

We conducted a case study of human immunodeficiency virus (HIV)-negative patients with cryptococcosis at 15 United States medical centers from 1990 through 1996 to understand the demographics, therapeutic approach, and factors associated with poor prognosis in this population. Of 306 patients with cryptococcosis, there were 109 with pulmonary involvement, 157 with central nervous system (CNS) i...

Cryptococcosis is a fungal infection caused by Cryptococcus neoformans that tends to affect immunocompromised individuals. The fungi are mostly acquired by inhalation, which leads to an initial pulmonary infection. Later, other organs - such as the central nervous system and the skin - can be affected by hematogenous spread. In addition, cutaneous contamination can occur by primary inoculation ...