BACKGROUND/AIMS To report a case of cutaneous malignant melanoma with cerebral metastasis found to have vitreoretinal metastasis upon referral for neovascular glaucoma. METHODS The clinical history and ocular examination findings, including histologic, cytologic, genetic, and immunohistochemical features of the vitreoretinal metastatic tumor, were reviewed. Additionally, the histologic and im...

Malignant melanoma is known for its protean cytomorphological features, architectural patterns, and stromal changes, in addition to its ability to mimic various benign and malignant non-melanocytic tumours. Anecdotal cases of metastatic malignant melanoma simulating soft tissue sarcomas have been reported. Interestingly, this mimicry is more often seen in recurrent lesions and metastatic deposi...

BACKGROUND Malignant melanoma arising from different body compartments may be associated with differing aetiological factors and clinical behaviour, and may manifest diverse molecular genetic profiles. Although many studies have focused on cutaneous melanoma, little is known of mucosal and other types of melanoma. In particular, malignant melanoma of soft parts is different from other melanomas...

Malignant melanoma arises by malignant transformation of the normal melanocytes. Distribution of malignant melanoma includes cutaneous (91.2%), ocular (5.3%), mucosal (1.3%), and unknown primary site (2.2%) [1]. Because of rarity and clinical challenges arising from different anatomic location, our understanding for the optimal management of mucosal melanoma remains limited. Malignant melanoma ...

Examination by ultrasonography (US) is a rapid, sensitive, cost-effective, and even portable technique for confirming the presence of tumors. However, US is not routinely used worldwide for the diagnostic work-up of cutaneous malignant melanoma. High-resolution US using a 6-14 MHz or 5-13 MHz linear transducer enables the preoperative assessment of tumor size and thickness. Compared with physic...

The relationship of epidermal urocanic acid concentration and photoisomerization reactivity to human skin cancer was studied. Twelve cutaneous malignant melanoma patients, 10 basal cell carcinoma patients and 22 healthy matched controls were enrolled in the study. A solar simulating ultraviolet irradiator was used for phototesting the minimal erythema dose. Using the Finn Chamber technique, uro...

zosteriform metastasis is a rare clinical distribution from spreading neoplasms of every organ to the skin. tumors most often arise from a n internal o r hematologic malignancy. w e report a 69-year-old man, a known case of malignant melanoma of the left heel. in this case, multiple red-brown metastatic nodules appeared four months after diagnosis. distribution of metastatic lesions resembled a...

Malignant melanoma of the larynx is a rare cancer that can appear as a primary tumor or as a metastasis from a cutaneous head and neck primary lesion. We present a new case of primary laryngeal malignant melanoma diagnosed by histological examination of an excisional biopsy specimen. The patient was a 53-year-old man with a history of smoking and hoarseness but without any clinical evidence of ...

We herein report a case of ileal invagination secondary to metastasis of a cutaneous melanoma. A 45-year-old female was admitted with intermittent abdominal pain and nausea. The patient's medical history was remarkable for cutaneous malignant melanoma. Imaging studies showed a solid mass in the right lower quadrant and the possibility of invagination. We made a preoperative diagnosis of partial...

Neurofibromatosis (NF) is a relatively common disorder characterized by cutaneous pigmented maculas, multiple neurofibromas and Lisch nodules (pigmented iris hamartomas). This disorder is retained being a neurocristopathy. Melanocytes are neural crest derivates too. Twenty-six patients with neurofibromatosis associated to cutaneous malignant melanoma have been reported till now, but data on ass...