Pulmonary arteriovenous malformation (PAVM) is a rare condition in which there is abnormal connection between pulmonary arteries and veins. The disorder usually appears in late childhood or early adult life, with dyspnea on exertion, clubbing or cyanosis. We present two patients with severe cyanosis and their work-up to diagnosis of PAVM, as a rare cause of cyanosis in childhood.

OBJECTIVES To examine the relationship between usual infant sleeping position and the parental report of infant cyanosis, pallor, breath-holding, and breathing difficulties; and to document hospital admission rates for apnea/cyanosis over time and to describe how admission rates vary by usual sleeping position. METHODS A prospective cohort study was conducted. It involved the one fifth of Tas...

We have stated in a preliminary report that the cyanosis observed in individuals treated with sulfanilamide is due to methemoglobin, and rarely, to sulfhemoglobin (1). We recognized at the time that attempts had been made to explain the presence of cyanosis on a different basis.. Marshall and Walzl (2) maintained that a black pigment derived from sulfanilamide, and present in the blood, was the...

congenital methemoglobinemia is a rare cause of cyanosis. we report a case of a girl, 17 years old with peripheral cyanosis and normal cardio-pulmonary system. she was diagnosed as a case of methemoglobinemia based on findings of polycythemia and hbm band on hemoglobin electrophoresis. we emphasize the importance of this rare entity in the differential diagnosis of cyanosis.

UNLABELLED One hundred and seventy three children, including 93 with biliary atresia, received liver grafts at Addenbrooke's Hospital between 1983 and 1993. Of these, only seven developed cyanosis due to intrapulmonary shunting as a complication of their liver disease, and all seven of these had the biliary atresia/polysplenia syndrome. Intrapulmonary shunting was confirmed by a radioisotope sc...

LARGE systemic arteriovenous fistulas are usually considered a form of acyanotic heart disease characterized by bounding pulses and cardiomegaly. This report deals with a cyanotic infant whose pulses were so weak that blood pressure was unobtainable either by the auscultatory or flush method. Although the infant died before hemodynamic studies were completed, we believe the cyanosis was due to ...