Cyclic deformation of metallic materials depends on the interaction multiple mechanisms across different length scales. Solid solution atoms, vacancies, grain boundaries, and forest dislocations interfere with dislocation glide increase macroscopic strength. In single phase under cyclic loading, localization densities in sessile substructures explains a significant fraction strain hardening. Up...

Corticostriatal synapse plasticity of medium spiny neurons is regulated by glutamate input from the cortex and dopamine input from the substantia nigra. While cortical stimulation alone results in long-term depression (LTD), the combination with dopamine switches LTD to long-term potentiation (LTP), which is known as dopamine-dependent plasticity. LTP is also induced by cortical stimulation in ...

A simple constitutive model for the inelastic response of steel under monotonic and random cyclic loading conditions is developed within the framework of bounding surface plasticity. The particular feature that distinguishes this model from other similar ones is the ability of the bounding surface formulation to describe in a very simple way the initial “plateau” type of perfectly plastic respo...

Concrete is a material whose performance is governed by the subtle interaction of its cohesive and frictional constituents. Since the theories of plasticity, damage mechanics, and fracture mechanics cannot, by themselves, capture both of these phenomena, a novel constitutive model is proposed which combines the theories of plasticity and damage mechanics in a multi-surface formulation. Synthesi...